IFN-beta

IFN-beta

IFN-beta 분자 정보

Molecule Name
Interferon beta
분자 별명
IFNB1,Interferon beta,IFN-beta,IFB,IFNB
Drug Development Progress
임상 약물 수6
시판 약물 수1
최고 연구 개발 단계Approved
표적 별명
Interferon Beta 1,Interferon, Beta 1, Fibroblast,IFNB,IFB,IFF,Interferon-beta,IFN-beta,Fibroblast interferon,IFNB1,Interferon beta
분자 배경
Interferon beta(IFN beta) is type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli. Signals via binding to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptor, activating the canonical Jak-STAT signaling pathway resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response, such as antiviral proteins, regulators of cell proliferation and differentiation, and immunoregulatory proteins. IFNB1 is more potent than interferon-alpha (IFN-alpha) in inducing the apoptotic and antiproliferative pathways required for control of tumor cell growth (By similarity)

IFN-beta 제품 목록

Species
  • Human(2)
  • Mouse(1)
Tag
  • His Tag & Avi Tag(2)
  • Fc Tag(1)
Host
  • HEK293(3)
Conjugate
  • Biotin-labeled(2)
  • Unconjugated(1)
Grade
  • RUO(3)
Low Endotoxin
  • No(3)
분자Cat. No.Product Name종Host구조순도Activity규격 및 가격
IFN-beta
Human IFN-beta Protein, Fc Tag (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$350.00

100ug
IFN-beta
Avitag
IFB-H82E4
Biotinylated Human IFN-beta Protein, His,Avitag™ (MALS & SPR verified)
Human
HEK293
MALSSDS-PAGE
SPR

$360.00

25ug
IFN-beta
Avitag
IFB-M82E3
Biotinylated Mouse IFN-beta Protein, His,Avitag™ (MALS & SPR verified)
Mouse
HEK293
MALSSDS-PAGE
SPR

$360.00

25ug
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임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
DazukibartPF-06823859Phase 3 ClinicalPfizer Inc
Dermatomyositis; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Muscular Diseases; Myositis; Polymyositis
상세
Peginterferon beta-1a (CinnaGen)Phase 3 ClinicalCinnagen
Multiple Sclerosis, Relapsing-Remitting
상세
VSV-IFNbeta-NISPhase 2 ClinicalVyriad
Angioimmunoblastic T-cell Lymphoma; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Endometrial Neoplasms; Histiocytoma; Leukemia, Myeloid, Acute; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Melanoma; Multiple Myeloma; Mycosis Fungoides; Myelodysplastic Syndromes; Sarcoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck
상세
VSV-hIFNbeta-NIS (University of Tennessee)Phase 1 ClinicalThe University Of Tennessee
Endometrial Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, T-Cell; Multiple Myeloma
상세
MEM-288MEM-288Phase 1 ClinicalMemgen
Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Melanoma; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Solid tumours; Triple Negative Breast Neoplasms
상세
SCD-153SCD-153Phase 1 ClinicalInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Johns Hopkins University, Sun Pharma Advanced Research Company Ltd
Alopecia Areata
상세

시판 약물 정보

영어 이름연구 코드연구 개발 단계회사가장 빠른 브랜드 이름가장 빠른 승인 국가가장 빠른 적응증가장 빠른 승인 회사가장 빠른 승인 날짜적응증임상 시험
PropagermaniumSK-818; SK-818CApprovedSanwa Kagaku Kenkyusho Co LtdSerocionJapanHepatitis BSanwa Kagaku Kenkyusho Co Ltd1994-01-01
Hepatitis B
상세
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