언어 선택

CTGF

CTGF 분자 정보

영어 이름	Connective tissue growth factor	시판 약물 수	1
임상 약물 수	5	표적 별명	Cellular communication network factor 2，IBP-8，Hypertrophic chondrocyte-specific protein 24，IGF-binding protein 8，IGFBP-8，Connective tissue growth factor，IGFBP8，CCN2，Insulin-like growth factor-binding protein 8，HCS24，CCN family member 2，CTGF，NOV2
최고 연구 개발 단계	Approved

영어 이름	Connective tissue growth factor
표적 별명	Cellular communication network factor 2，IBP-8，Hypertrophic chondrocyte-specific protein 24，IGF-binding protein 8，IGFBP-8，Connective tissue growth factor，IGFBP8，CCN2，Insulin-like growth factor-binding protein 8，HCS24，CCN family member 2，CTGF，NOV2
시판 약물 수	1
임상 약물 수	5
최고 연구 개발 단계	Approved

CTGF 제품 목록

속성
Protein (5)
제품 라이브러리
온라인 (5)
종
Human (3)Mouse (1)Rhesus macaque (1)
태그
His Tag & Avi Tag (1)His Tag (3)Fc Tag (1)
마커
Biotin-labeled (1)Unconjugated (4)

제품 번호	종	발현 시스템	제품 설명
HOT CTF-H52H5	Human	HEK293	Human CTGF / CCN2 Protein, His Tag
HOT CTF-H82E6	Human	HEK293	Biotinylated Human CTGF / CCN2 Protein, His,Avitag™ (recommended for biopanning)
HOT GTF-H5253	Human	HEK293	Human CTGF / CCN2 Protein, Fc Tag
HOT GTF-R52H4	Rhesus macaque	HEK293	Rhesus macaque CTGF / CCN2 Protein, His Tag
CTF-M52Hc	Mouse	HEK293	Mouse CTGF / CCN2 Protein, His Tag

총 수량5

CTGF분자 배경

Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.

CTGF분자 별명

CCN2,NOV2,HCS24,IGFBP8,IBP-8,IGFBP-8,IGF-binding protein 8

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Pamrevlumab	FG-3019	Phase 3 Clinical	Fibrogen Inc	Coronavirus Disease 2019 (COVID-19); Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerulosclerosis, Focal Segmental; Idiopathic Pulmonary Fibrosis; Liver Cirrhosis; Muscular Dystrophy, Duchenne; Pancreatic Neoplasms	상세
OLX-10010	cp-asiCTGF; OLX-101A; OLX-10010; BMT-101; OLX-101	Phase 2 Clinical	Olix Pharmaceuticals Inc	Cicatrix, Hypertrophic; Macular Degeneration; Pulmonary Fibrosis; Wet Macular Degeneration	상세
SHR-1906	SHR-1906	Phase 2 Clinical	Guangdong Hengrui Pharmaceutical Co Ltd	Idiopathic Pulmonary Fibrosis	상세
PRS-220	PRS-220	Phase 1 Clinical	Pieris Pharmaceuticals	Idiopathic Pulmonary Fibrosis	상세
LEM-S401	LEM-S401; LEMS401	Phase 1 Clinical	Lemonex Inc	Cicatrix	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Penicillamine		Approved	Valeant	Distamine, Pemine, Trisorcin, Cuprimine, Cupramine, Trolovol	United States	Arthritis, Rheumatoid; Hepatolenticular Degeneration; Cystinuria	Bausch Health Companies Inc	1970-12-04	Arthritis, Rheumatoid; Cystinuria; Heavy Metal Poisoning; Hepatolenticular Degeneration; Lead Poisoning	상세