Mouse CTGF / CCN2 Protein, His Tag

사용자 리뷰
제품 번호/규격
가격
수량
CTF-M52Hc-100ug
$395.00
CTF-M52Hc-1mg (250ug X 4)
$2615.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    CCN2, NOV2, HCS24, IGFBP8, IBP-8, IGFBP-8, IGF-binding protein 8

  • Source

    Mouse CTGF, His Tag (CTF-M52Hc) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Ala 348 (Accession # P29268-1).

    Predicted N-terminus: Gln 26

    Request for sequence
  • Molecular Characterization

    CTGF Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 37.3 kDa. The protein migrates as 37-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in Tris with Potassium glutamate and Arginine, pH7.0 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    CTGF SDS-PAGE

    Mouse CTGF, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • Bioactivity-ELISA

     CTGF ELISA

    Immobilized Mouse CTGF, His Tag (Cat. No. CTF-M52Hc) at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CTGF Antibody, Human IgG1 with a linear range of 0.3-5 ng/mL (QC tested).

    Protocol
  • Bioactivity-BLI

     CTGF BLI

    Loaded Monoclonal Anti-Human CTGF Antibody, Human IgG1 on AHC Biosensor, can bind Mouse CTGF, His Tag (Cat. No. CTF-M52Hc) with an affinity constant of 2.46 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

    Protocol

사용자 리뷰
댓글 남기기

배경 소개

Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced D synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Connective tissue growth factor

  • 카테고리:

  • 상장 의약품 수:

    1 상세

  • 임상 의약품 수:

    5 상세

  • 최고 개발 단계:

    Approved

연락하기
신약 후보물질 라이선싱
더 많이 알아보기
  • 기본 제품 정보
  • 제품 세부정보
  • 고객님도 확인한 상품
  • 데이터 표시
  • 사용자 리뷰
  • 배경
문의하기

전화
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521

주소 서울특별시 송파구 법원로11길 11, 제3층 제비-314,315호