Select Language

Properdin

Properdin Overview

English Name	Properdin	Approved Drugs	0
Drugs in Clinical Trials	2	Target Synonym	Complement factor P，CFP
Highest Development Stage	Phase 2 Clinical

English Name	Properdin
Target Synonym	Complement factor P，CFP
Approved Drugs	0
Drugs in Clinical Trials	2
Highest Development Stage	Phase 2 Clinical

Properdin Product List

Product Category
Protein (3)
Product Status
Launched (3)
Species
Human (1)Mouse (1)Rhesus macaque (1)
Tag
His Tag (3)
Conjugate
Unconjugated (3)

Cat. No.	Species	Host	Product Description
HOT PRN-H52H3	Human	HEK293	Human Properdin Protein, His Tag
PRN-M52H5	Mouse	HEK293	Mouse Properdin Protein, His Tag
PRN-R52H6	Rhesus macaque	HEK293	Rhesus macaque Properdin Protein, His Tag

Total: 3

Properdin Background

Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.

Properdin Synonyms

Properdin,Complement factor P,CFP,PFC

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Tarperprumig	ALXN-1820	Phase 2 Clinical	Alexion Pharmaceuticals Inc	Anemia, Sickle Cell; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	Details
NM-5072	NM5072; NM-5072	Phase 1 Clinical	NovelMed Therapeutics Inc	Atypical Hemolytic Uremic Syndrome; Eye Diseases; Hemoglobinuria, Paroxysmal	Details