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MBL

MBL Overview

English Name	Mannose-binding protein C	Approved Drugs	0
Drugs in Clinical Trials	1	Target Synonym	Mannose Binding Lectin 2，Mannose-Binding Lectin (Protein C) 2， Soluble (Opsonic Defect)，MBL，Mannose-Binding Lectin 2， Soluble (Opsonic Defect)，Mannose-Binding Lectin (Protein C) 2， Soluble，Mannan-Binding Protein，Mannan-Binding Lectin，HSMBPC，MBL2D，MBPD，MBP，Mannose-Binding Lectins，Mannose-Binding Protein，MBP1，COLEC1，Mannose-binding protein C，Mannose-binding lectin，Collectin-1，MBP-C，MBL2
Highest Development Stage	Clinical

English Name	Mannose-binding protein C
Target Synonym	Mannose Binding Lectin 2，Mannose-Binding Lectin (Protein C) 2， Soluble (Opsonic Defect)，MBL，Mannose-Binding Lectin 2， Soluble (Opsonic Defect)，Mannose-Binding Lectin (Protein C) 2， Soluble，Mannan-Binding Protein，Mannan-Binding Lectin，HSMBPC，MBL2D，MBPD，MBP，Mannose-Binding Lectins，Mannose-Binding Protein，MBP1，COLEC1，Mannose-binding protein C，Mannose-binding lectin，Collectin-1，MBP-C，MBL2
Approved Drugs	0
Drugs in Clinical Trials	1
Highest Development Stage	Clinical

MBL Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
MBL-H5220	Human	HEK293	Human MBL Protein, His Tag

Total: 1

MBL Background

Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.