언어 선택

LIGHT

LIGHT 분자 정보

영어 이름	Tumor necrosis factor superfamily member 14	시판 약물 수	0
임상 약물 수	1	표적 별명	CD258 Antigen，Herpes Virus Entry Mediator Ligand，TNFSF14，Herpesvirus Entry Mediator Ligand，LIGHT，Tumor Necrosis Factor (Ligand) Superfamily， Member 14，CD258，HVEM-L，Tumor Necrosis Factor Ligand 1D，LTg，HVEML，TNF Superfamily Member 14，Tumor Necrosis Factor Ligand Superfamily Member 14，Tumor Necrosis Factor Superfamily Member 14
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Tumor necrosis factor superfamily member 14
표적 별명	CD258 Antigen，Herpes Virus Entry Mediator Ligand，TNFSF14，Herpesvirus Entry Mediator Ligand，LIGHT，Tumor Necrosis Factor (Ligand) Superfamily， Member 14，CD258，HVEM-L，Tumor Necrosis Factor Ligand 1D，LTg，HVEML，TNF Superfamily Member 14，Tumor Necrosis Factor Ligand Superfamily Member 14，Tumor Necrosis Factor Superfamily Member 14
시판 약물 수	0
임상 약물 수	1
최고 연구 개발 단계	Phase 2 Clinical

LIGHT 제품 목록

속성
Protein (6)Cell (1)
제품 라이브러리
온라인 (7)
종
Human (5)Cynomolgus (1)Mouse (1)
태그
Mouse IgG Fc Tag (1)His Tag (4)Fc Tag (1)- (1)
마커
Unconjugated (6)- (1)

제품 번호	종	발현 시스템	제품 설명
HOT LIT-H5242	Human	HEK293	Human LIGHT / TNFSF14 Protein, His Tag, active trimer, low endotoxin (MALS verified)
HOT LIT-H5269	Human	HEK293	Human LIGHT / TNFSF14 Protein, Fc Tag, active trimer, low endotoxin (MALS verified)
HOT LIT-M5243	Mouse	HEK293	Mouse LIGHT / TNFSF14 Protein, His Tag, active trimer (MALS verified)
HOT LIT-C5244	Cynomolgus	HEK293	Cynomolgus LIGHT / TNFSF14 Protein, His Tag, active trimer, low endotoxin (MALS verified)
LIT-H5243	Human	HEK293	Human LIGHT / TNFSF14 Protein, His Tag, Ultra Low Endotoxin (MALS verified)
LIT-H5256	Human	HEK293	Human LIGHT / TNFSF14 Protein, Mouse IgG2a Fc Tag, low endotoxin
SCCHO-ATP109	Human	CHO	CHO/Human LIGHT Stable Cell Line

총 수량7

LIGHT분자 배경

Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.

LIGHT분자 별명

CD258 antigen,CD258,HVEM-L,LIGHT,LTg,TNFSF14,TR2,HVEML

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Quisovalimab	CERC-002; AEVI-002; MDGN-002; SAR-252067; AVTX-002	Phase 2 Clinical	Kyowa Hakko Kirin Co Ltd, La Jolla Pharmaceutical Company	Acute Lung Injury; Asthma; Colitis, Ulcerative; Coronavirus Disease 2019 (COVID-19); Crohn Disease; Respiratory Distress Syndrome, Adult	상세

제품 리뷰

E***a2021-09-23
1사람들이 좋아합니다
Human LIGHT / TNFSF14 Protein, His Tag, active trimer, low endotoxin (MALS verified)
We use this protein as an ELISA standard. We are interested in quantifying soluble LIGHT concentration from human serum. This active form of the protein perfectly binds its receptors and policlonal antibodies. The standard curve obtained is highly reproducible. It was very easy to find all the information in the web of AcroBiosystems and to download the CoA, which was also very descriptive.