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IL-24

IL-24 Overview

English Name	Interleukin 24	Approved Drugs	0
Drugs in Clinical Trials	1	Target Synonym	ST16，Interleukin-24，IL24，MDA-7，Suppression of tumorigenicity 16 protein，IL-24，Interleukin 24，Suppression Of Tumorigenicity 16 (Melanoma Differentiation)，Melanoma Differentiation-Associated Gene 7 Protein，IL-4-Induced Secreted Protein，MDA7，Melanoma Differentiation Association Protein 7，Melanocyte-Associated Mda-7，IL10B，C49A，FISP，MOB5，Mob-5
Highest Development Stage	Phase 1 Clinical

English Name	Interleukin 24
Target Synonym	ST16，Interleukin-24，IL24，MDA-7，Suppression of tumorigenicity 16 protein，IL-24，Interleukin 24，Suppression Of Tumorigenicity 16 (Melanoma Differentiation)，Melanoma Differentiation-Associated Gene 7 Protein，IL-4-Induced Secreted Protein，MDA7，Melanoma Differentiation Association Protein 7，Melanocyte-Associated Mda-7，IL10B，C49A，FISP，MOB5，Mob-5
Approved Drugs	0
Drugs in Clinical Trials	1
Highest Development Stage	Phase 1 Clinical

IL-24 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
IL4-H52H4	Human	HEK293	Human IL-24 Protein, His Tag (BLI verified)

Total: 1

IL-24 Background

Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26. Interleukin 24 signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. Upon binding to its receptors, IL-24 induces rapid activation of Stat-1 and Stat-3 transcription factors, which appear to play a role in cell survival and proliferation . Structurally and functionally, IL-24 is highly conserved across species.IL-24 has been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent.