언어 선택

GITR

GITR 분자 정보

영어 이름	Glucocorticoid-induced tumor necrosis factor receptor-related protein	시판 약물 수	0
임상 약물 수	4	표적 별명	TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Glucocorticoid-induced tumor necrosis factor receptor-related protein
표적 별명	TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18
시판 약물 수	0
임상 약물 수	4
최고 연구 개발 단계	Phase 2 Clinical

GITR 제품 목록

속성
Protein (7)
제품 라이브러리
온라인 (7)
종
Human (4)Canine (1)Mouse (2)
태그
His Tag (3)Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (2)
마커
Unconjugated (4)Biotin-labeled (3)

제품 번호	종	발현 시스템	제품 설명
HOT GIR-H5228	Human	HEK293	Human GITR / TNFRSF18 Protein, His Tag, low endotoxin (MALS verified)
HOT GIR-H5254	Human	HEK293	Human GITR / TNFRSF18 Protein, Fc Tag, low endotoxin
GIR-H82E5	Human	HEK293	Biotinylated Human GITR / TNFRSF18 Protein, His,Avitag™ (MALS verified)
GIR-H82F7	Human	HEK293	Biotinylated Human GITR / TNFRSF18 Protein, Fc,Avitag™
GIR-M52H3	Mouse	HEK293	Mouse GITR / TNFRSF18 Protein, His Tag
GIR-M82E3	Mouse	HEK293	Biotinylated Mouse GITR / TNFRSF18 Protein, His,Avitag™ (MALS verified)
GIR-C52H6	Canine	HEK293	Canine GITR / TNFRSF18 Protein, His Tag

총 수량7

GITR분자 배경

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

GITR분자 별명

AITR,GITR,TNFRSF18,CD357

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
BMS-986156	BMS-986156	Phase 2 Clinical	Bristol-Myers Squibb Company	Liver Neoplasms; Lung Neoplasms; Neoplasms; Solid tumours; Thoracic Neoplasms	상세
Ragifilimab	INCAGN-1876; INCAGN-01876; AGEN-1876; CM-701	Phase 2 Clinical	Agenus Inc, Ludwig Institute For Cancer Research	Neoplasm Metastasis; Neoplasms	상세
Anti-GITR antibody (BMS)		Phase 1 Clinical	Bristol-Myers Squibb Company	Neoplasms	상세
IBI-102	IBI102; IBI-102	Phase 1 Clinical		Neoplasms	상세

제품 리뷰

1***32019-09-27
1사람들이 좋아합니다
Human GITR / TNFRSF18 Protein, His Tag, low endotoxin (MALS verified)
I have been using Acro's products for a long time. Whenever there is some concerns on product or technical support is needed, it always gets solved in time. I used the GITR protein for SPR experiments. I have done 6 concentration gradients, and the fitted curve was still very good. The data also met my expectations. I hope we will continue having a good cooperation with ACRO moving forward.