언어 선택

FGF basic

FGF basic 분자 정보

영어 이름	Fibroblast growth factor 2	시판 약물 수	1
임상 약물 수	4	표적 별명	FGF-2，Heparin-binding growth factor 2，Basic fibroblast growth factor，FGFB，bFGF，HBGF-2，FGF2，Fibroblast Growth Factor 2 (Basic)，Basic Fibroblast Growth Factor BFGF，Prostatropin，Fibroblast Growth Factor 2
최고 연구 개발 단계	Approved

영어 이름	Fibroblast growth factor 2
표적 별명	FGF-2，Heparin-binding growth factor 2，Basic fibroblast growth factor，FGFB，bFGF，HBGF-2，FGF2，Fibroblast Growth Factor 2 (Basic)，Basic Fibroblast Growth Factor BFGF，Prostatropin，Fibroblast Growth Factor 2
시판 약물 수	1
임상 약물 수	4
최고 연구 개발 단계	Approved

FGF basic 제품 목록

속성
Protein (7)Kits (1)
제품 라이브러리
온라인 (8)
종
Human (8)
태그
Tag Free (6)His Tag & Avi Tag (1)- (1)
마커
Unconjugated (6)Biotin-labeled (1)- (1)

제품 번호	종	발현 시스템	제품 설명
HOT BFF-H4117	Human	E. coli	Human FGF basic Protein, premium grade
HOT BFF-H5115	Human	E. coli	Human FGF basic (154aa) Protein, premium grade
HOT GMP-FGCH17	Human	E. coli	GMP Human FGF basic Protein
BFF-H4118	Human	E. coli	Human FGF basic Protein, Research Grade
BFF-H5113	Human	E. coli	Human FGF basic Superior Stable Mutant Protein, premium grade
BFF-H5114	Human	E. coli	Human FGF basic Superior Stable Mutant Protein, Research Grade
CEA-C082	Human	-	Human bFGF/FGF2 ELISA Kit
FGC-H81E3	Human	E. coli	Biotinylated Human FGF basic Protein, Avitag™,His Tag (HPLC verified)

총 수량8

FGF basic분자 배경

FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35-60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. FGF basic has been isolated from a number of sources, including neural tissue, pituitary, adrenal cortex, corpus luteum, and placenta. This factor contains four cysteine residues, but reduced FGF basic retains full biological activity, indicating that disulfide bonds are not required for this activity. bFGF is a critical component of human embryonic stem cell culture medium; the growth factor is necessary for the cells to remain in an undifferentiated state, although the mechanisms by which it does this are poorly defined. It has been demonstrated to induce gremlin expression which in turn is known to inhibit the induction of differentiation by bone morphogenetic proteins. It is necessary in mouse-feeder cell dependent culture systems, as well as in feeder and serum-free culture systems.

FGF basic분자 별명

FGF2,BFGF,FGFB,FGF basic,HBGF-2

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Muparfostat sodium	PI-88	Phase 3 Clinical	Australian National University	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liver Neoplasms; Lung Neoplasms; Melanoma; Neoplasms; Prostatic Neoplasms; Skin Melanoma; Solid tumours	상세
RBM-007	ID3 (21); APT-F2; RBM-007	Phase 2 Clinical	Ribomic	Achondroplasia; Macular Degeneration	상세
Fibroblast growth factor 2 gene therapy (ID Pharma)	SeV-10101; SEV-10101; DVC-10101; BF-30	Phase 2 Clinical	Dnavec	Arterial Occlusive Diseases; Intermittent Claudication; Ischemia; Peripheral Arterial Disease; Peripheral arterial occlusive disorders	상세
Recombinant Human Epidermal Growth Factor Derivative Gel (Uni-Bio Science)		Phase 1 Clinical	Uni-Bio Science Group	Wounds and Injuries	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Thalidomide	NSC-66847; NSC-527179; K-17; FPF-300; FPF300	Approved	Celgene Corp	Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled	Mainland China	Leprosy, Lepromatous; Multiple Myeloma	Changzhou Pharmaceutical Factory	1982-01-01	Acquired Immunodeficiency Syndrome; Adenocarcinoma, Clear Cell; Adenoma, Islet Cell; Amyotrophic Lateral Sclerosis; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sideroblastic; Angiodysplasia; Appendiceal Neoplasms; Arachnoiditis; Arteriovenous Malformations; Axial Spondyloarthritis; beta-Thalassemia; Burning Mouth Syndrome; Carcinoid Tumor; Carcinoma, Adenosquamous; Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Colorectal Neoplasms; Cough; Endometrial Neoplasms; Endometriosis; Epilepsy; Erythema Nodosum; Gastric Antral Vascular Ectasia; Gastrointestinal Hemorrhage; Genetic Diseases, Inborn; Glioma; Graft vs Host Disease; Head and Neck Neoplasms; Hemoglobinopathies; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Hormone-Resistant Prostate Neoplasms; Hypertension, Portal; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Leiomyosarcoma; Leprosy, Lepromatous; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Chronic; Liver Neoplasms; Lung Neoplasms	상세