언어 선택

DR3

DR3 제품 목록

속성
Protein (7)Cell (1)
제품 라이브러리
온라인 (8)
종
Cynomolgus (2)Human (5)Mouse (1)
태그
Fc Tag (2)His Tag (3)- (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (1)
마커
Unconjugated (5)- (1)Biotin-labeled (2)

제품 번호	종	발현 시스템	제품 설명
HOT DR3-H5253	Human	HEK293	Human DR3 Protein, Fc Tag, low endotoxin (MALS verified)
HOT DR3-H82E3	Human	HEK293	Biotinylated Human DR3 / TNFRSF25 Protein, His,Avitag™ (MALS verified)
HOT TN5-H52H3	Human	HEK293	Human DR3 / TNFRSF25 Protein, His Tag, low endotoxin (MALS verified)
DR3-H82F3	Human	HEK293	Biotinylated Human DR3 / TNFRSF25 Protein, Fc,Avitag™ (MALS verified)
SCJUR-STF178	Human	Jurkat	Human DR3 (TL1A receptor) (Luc) Jurkat Reporter Cell
DR3-M52H3	Mouse	HEK293	Mouse DR3 / TNFRSF25 Protein, His Tag, low endotoxin (HPLC & SPR verified)
DR3-C52H3	Cynomolgus	HEK293	Cynomolgus DR3 / TNFRSF25 Protein, His Tag, low endotoxin (SPR verified)
TN5-C5257	Cynomolgus	HEK293	Cynomolgus DR3 / TNFRSF25 Protein, Fc Tag, low endotoxin

총 수량8

DR3분자 배경

Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Ontamalimab	SHP-647; PF-00547659; PF-547659	Phase 3 Clinical	Pfizer Inc	Ileitis; Colitis, Ulcerative; Crohn Disease	상세
Vedolizumab biosimilar (Polpharma Biologics)	PB-016	Phase 3 Clinical	Polpharma Biologics Sa	Pouchitis; Colitis, Ulcerative; Crohn Disease	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Vedolizumab	MLN-0002; LPD-02; MLN-002; MLN-02; LDP-02	Approved	Millennium Pharmaceuticals Inc	安吉优, Entyvio	United States	Colitis, Ulcerative; Crohn Disease	Takeda Pharmaceuticals USA Inc	2014-05-20	Celiac Disease; Carcinoma, Non-Small-Cell Lung; Melanoma; Crohn Disease; Gastritis; Urogenital Neoplasms; Colitis, Ulcerative; Cholangitis, Sclerosing; Pediatric ulcerative colitis; Solid tumours; Colitis; Pouchitis; Neoplasms; Pediatric Crohn's disease; Inflammatory Bowel Diseases; HIV Infections; Hematopoietic stem cell transplantation (HSCT)	상세