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Coagulation factor VII

Coagulation factor VII

Coagulation factor VII 분자 정보

Molecule Name
Coagulation factor VII
분자 별명
Coagulation factor VII,F7,SPCA,Proconvertin
Drug Development Progress
임상 약물 수8
시판 약물 수22
최고 연구 개발 단계Approved
표적 별명
EC 3.4.21，Eptacog alfa，F7，Coagulation Factor VII，Coagulation Factor VII (Serum Prothrombin Conversion Accelerator)，FVII Coagulation Protein，SPCA，EC 3.4.21.21，Factor VII，Proconvertin，Serum prothrombin conversion accelerator，EC:3.4.21.21
분자 배경
Coagulation factor VII is also known as F7, SPCA and Proconvertin. Heterodimer of a light chain and a heavy chain linked by a disulfide bond. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.

Coagulation factor VII 제품 목록

Species
  • Human（1）
  • Mouse（1）
Tag
  • His Tag（2）
Host
  • HEK293（2）
Conjugate
  • Unconjugated（2）
Grade
  • RUO（2）
Low Endotoxin
  • No（2）
분자Cat. No.Product Name종Host구조순도Activity규격 및 가격
Coagulation factor VII
COI-M52H1
Mouse Coagulation factor VII Protein, His Tag (Pro-form, MALS verified)
Mouse
HEK293
MALSSDS-PAGE
Enzyme

$410.00

20ug
Coagulation factor VII
TF7-H52H5
Human Coagulation factor VII / F7 Protein, His Tag (Pro-form, MALS verified)
Human
HEK293
MALSSDS-PAGE
Enzyme

$410.00

20ug
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임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
Human prothrombin complex (National Drug Group Wuhan Blood)Phase 3 ClinicalSinopharm Wuhan Biopharmaceutical Co Ltd
Hemophilia B; Hemorrhage
상세
Human prothrombin complex concentrate (Sichuan Yuanda Shuyang Pharmaceutical)Phase 3 ClinicalYuanda Shuyang Life Sciences (Chengdu) Co Ltd
Blood Coagulation Disorders
상세
Human prothrombin complex concentrate (Harbin Shiheng Bioengineering Pharmaceutical)Phase 3 ClinicalHarbin Pacific Biopharmaceutical Co Ltd
Hemophilia B
상세
Human prothrombin complex(Hunan Ziguang Huhan Nanyue Pharmaceutical)Phase 3 ClinicalHunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd
Hemophilia B
상세
Factor VII (KM Biologics)KD2-305Phase 3 ClinicalKM Biologics Co Ltd
Hemophilia A
상세
SutacimigHMB001; HMB-001Phase 2 ClinicalHemab Therapeutics APS
Factor VII Deficiency; Thrombasthenia
상세
SIG-001(Sigilon)Sig-001(Sigilon)Phase 2 ClinicalSigilon Therapeutics Inc
Hemophilia A
상세
recombinant coagulation factor VIIa (Chengdu Rongsheng Pharmaceuticals)Phase 1 ClinicalChengdu Rongsheng Pharmaceuticals Co Ltd
Hemophilia A; Hemophilia B
상세

시판 약물 정보

영어 이름연구 코드연구 개발 단계회사가장 빠른 브랜드 이름가장 빠른 승인 국가가장 빠른 적응증가장 빠른 승인 회사가장 빠른 승인 날짜적응증임상 시험
Anti-inhibitor coagulant complex (Baxalta)ApprovedBaxalta IncorporatedPROPLEX 600, Prothromplex, Prothromplex 600, Prothromplex 600 IE, Prothromplex 600 SV, Prothromplex 600 TV, Prothromplex 600 UI, Prothromplex NF 600, PROPLEX, Feiba, Prothromplex TOTALUnited StatesHemophilia B; Hemophilia ABaxalta Incorporated1979-12-21
Blood Coagulation Disorders; Blood Coagulation Disorders, Inherited; Cardiovascular Diseases; Heart Diseases; Hemophilia A; Hemophilia B; Hemorrhage
상세
Human prothrombin complex (Nanyue Biopharming)ApprovedHunan Ziguang Huhan Nanyue Pharmaceutical Co LtdMainland ChinaHemorrhageHunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd2019-09-05
Hemophilia B; Hemorrhage
상세
Human prothrombin complex (CSL Behring)BE-1116ApprovedCsl Behring LlcKcentra, Beriplex, ConfidexJapanVitamin K Deficiency BleedingCsl Behring Kk
Blood Coagulation Disorders; Coagulation Protein Disorders; Heart Diseases; Heart Failure; Hemorrhage; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Vitamin K Deficiency Bleeding; Wounds and Injuries
상세
Human prothrombin complex concentrate (Guizhou Taibang Biological Products)ApprovedGuizhou Taibang Biological Products Co LtdMainland ChinaHypoprothrombinemiasGuizhou Taibang Biological Products Co Ltd2013-07-31
Hypoprothrombinemias
상세
Prothrombinex-VF (CSL Behring)ApprovedCsl Behring LlcAustraliaHemorrhageCsl Behring Llc2014-10-01
Hemorrhage
상세
Prothrombin complex concentrate (Sanquin)ApprovedSanquin Plasma Products BvCofactHemorrhageSanquin Plasma Products Bv2007-11-01
Hemorrhage
상세
Factor IX complex (Grifols)ApprovedGrifols SaProfilnineUnited StatesHemophilia Bnull1981-07-21
Hemophilia B; Intracranial Hemorrhages
상세
Human prothrombin complex (Octapharma)ApprovedOctapharmaOcplex, Octaplex, PronativGermanyHemorrhageOctapharma2003-03-14
Hemorrhage; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
상세
Human prothrombin complex (LFB)ApprovedLfb Biotechnologies SasKANOKADFranceHemorrhageLfb Biotechnologies Sas2008-09-01
Hemorrhage
상세
Human prothrombin complex (Tonrol Biopharmaceuticals)ApprovedTonrol Bio-Pharmaceutical Co LtdProthoRAASMainland ChinaHemorrhageShanghai Raas Blood Products Co Ltd1996-01-01
Hemophilia B; Hemorrhage
상세
Human prothrombin complex (ShenzhenWeiguang Biological Products)ApprovedShenzhen Weiguang Biological Products Co LtdMainland ChinaHemorrhageShenzhen Weiguang Biological Products Co Ltd2024-05-21
Hemophilia B; Hemorrhage
상세
Human prothrombin complex (Guangdong Shuanglin)ApprovedGuangdong Shuanglin Bio-Pharmaceutical Co LtdMainland ChinaHemophilia BGuangdong Shuanglin Bio-Pharmaceutical Co Ltd2023-05-12
Hemophilia B
상세
Human prothrombin complex (Shanghai Xinxing)ApprovedShanghai Xinxing Medicine Co LtdMainland ChinaHemorrhageShanghai Xinxing Medicine Co Ltd1997-01-01
Hemorrhage
상세
Human prothrombin complex (Sinopharm Shanghai Plasma)ApprovedSinopharm Shanghai Plasma-Derived Biotherapies Co LtdMainland ChinaHemorrhageSinopharm Shanghai Plasma-Derived Biotherapies Co Ltd1997-01-01
Hemorrhage
상세
Human prothrombin complex (Boya Bio-Pharmaceutical)ApprovedBoya Bio-Pharmaceutical Group Co LtdMainland ChinaHemorrhageBoya Bio-Pharmaceutical Group Co Ltd2020-12-02
Hemophilia B; Hemorrhage
상세
Human prothrombin complex (Guangdong Wellen)ApprovedGuangdong Wellen Pharmaceutical Co LtdMainland ChinaHemorrhageGuangdong Wellen Pharmaceutical Co Ltd2020-10-21
Hemophilia B; Hemorrhage
상세
Human prothrombin complex (Lanzhou Lansheng Blood Products)ApprovedLanzhou Lansheng Blood Products Co LtdMainland ChinaHemophilia BLanzhou Lansheng Blood Products Co Ltd2024-09-26
Hemophilia B
상세
Human prothrombin complex(Chengdu Rongsheng Pharmaceuticals)ApprovedChengdu Rongsheng Pharmaceuticals Co LtdMainland ChinaCoagulation Protein DisordersChengdu Rongsheng Pharmaceuticals Co Ltd2020-12-15
Coagulation Protein Disorders; Hemophilia B
상세
Human prothrombin complex(Hebei Daan Pharmaceutical)ApprovedHebei Daan Pharmaceutical Co LtdMainland ChinaHemorrhageHebei Daan Pharmaceutical Co Ltd2020-01-01
Hemophilia B; Hemorrhage
상세
Prothrombin complex concentrat (Taibang Biological Products)ApprovedShandong Taibang Biological Products Co LtdMainland ChinaHemorrhageShandong Taibang Biological Products Co Ltd2014-09-30
Antithrombin III Deficiency; Hemorrhage
상세
Human prothrombin complex (Hualan Biological Engineering)ApprovedHualan Ankang Biotechnology Co LtdMainland ChinaFactor X Deficiency; Blood Coagulation DisordersHualan Biological Engineering Inc1999-01-01
Blood Coagulation Disorders; Factor X Deficiency; Hemophilia B
상세
Human prothrombin complex concentrate (Shanxi Kangbao Biological Products)ApprovedShanxi Kangbao Biological Product Co LtdMainland ChinaHemorrhageShanxi Kangbao Biological Product Co Ltd2019-09-17
Hemophilia B; Hemorrhage
상세
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