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CD59

CD59 분자 정보

영어 이름	CD59 glycoprotein	시판 약물 수	0
임상 약물 수	1	표적 별명	CD59 Antigens，Membrane attack complex inhibition factor，Membrane inhibitor of reactive lysis，MEM43 antigen，HRF-20，MIRL，20 kDa homologous restriction factor，MAC-inhibitory protein，MACIF，Protectin，MAC-IP，1F5 antigen，P18-20，CD59 Molecule， Complement Regulatory Protein，MSK21，CD59 Antigen， Complement Regulatory Protein，16.3A5，Lymphocytic Antigen CD59/MEM43，MIC11，MIN1，Ly-6-Like Protein，1F5，T Cell-Activating Protein，CD59 Antigen，EJ30，MIN2，MIN3，EL32，Surface Anitgen Recognized By Monoclonal Antibody 16.3A5，MEM43，EJ16，G344，CD59 Molecule (CD59 Blood Group)，Membrane Attack Complex (MAC) Inhibition Factor，CD59 Molecule，CD59 Antigen P18-20 (Antigen Identified By Monoclonal Antibodies 16.3A5， EJ16， EJ30， EL32 And G344)，Human Leukocyte Antigen MIC11，HRF20，CD59 Blood Group Antigen
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	CD59 glycoprotein
표적 별명	CD59 Antigens，Membrane attack complex inhibition factor，Membrane inhibitor of reactive lysis，MEM43 antigen，HRF-20，MIRL，20 kDa homologous restriction factor，MAC-inhibitory protein，MACIF，Protectin，MAC-IP，1F5 antigen，P18-20，CD59 Molecule， Complement Regulatory Protein，MSK21，CD59 Antigen， Complement Regulatory Protein，16.3A5，Lymphocytic Antigen CD59/MEM43，MIC11，MIN1，Ly-6-Like Protein，1F5，T Cell-Activating Protein，CD59 Antigen，EJ30，MIN2，MIN3，EL32，Surface Anitgen Recognized By Monoclonal Antibody 16.3A5，MEM43，EJ16，G344，CD59 Molecule (CD59 Blood Group)，Membrane Attack Complex (MAC) Inhibition Factor，CD59 Molecule，CD59 Antigen P18-20 (Antigen Identified By Monoclonal Antibodies 16.3A5， EJ16， EJ30， EL32 And G344)，Human Leukocyte Antigen MIC11，HRF20，CD59 Blood Group Antigen
시판 약물 수	0
임상 약물 수	1
최고 연구 개발 단계	Phase 2 Clinical

CD59 제품 목록

속성
Protein (2)
제품 라이브러리
온라인 (2)
종
Human (2)
태그
His Tag (1)His Tag & Avi Tag (1)
마커
Unconjugated (1)Biotin-labeled (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
CD9-H52H9	Human	HEK293	Human CD59 Protein, His Tag
CD9-H82E3	Human	HEK293	Biotinylated Human CD59 Protein, His,Avitag™

총 수량2

CD59분자 배경

CD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL. CD59 has been identified as a glycosylphosphatidylinositol-anchored membrane protein that acts as an inhibitor of the formation of the membrane attack complex to regulate complement activation. Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

CD59분자 별명

CD59,16.3A5,1F5,EJ16,EJ30,EL32,FLJ38134,FLJ92039,G344,HRF20,MAC-IP,MACIF,MEM43,MGC2354,MIC11,MIN1,MIN2,MIN3,MIRL,MSK21,p18-20,Protectin

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Onzemipgene Parvec	HMR-59; AAVCAGsCD59; JNJ-81201887; JNJ-1887	Phase 2 Clinical	Tufts University	Geographic Atrophy; Macular Degeneration; Pyruvate kinase deficiency	상세