언어 선택

CD47

CD47 분자 정보

영어 이름	Cluster of differentiation 47	시판 약물 수	0
임상 약물 수	48	표적 별명	MER6，CD47，Leukocyte surface antigen CD47，CD47 Molecule，Antigenic Surface Determinant Protein OA3，CD47 Antigen (Rh-Related Antigen， Integrin-Associated Signal Transducer)，Antigen Identified By Monoclonal Antibody 1D8，Integrin Associated Protein，Rh-Related Antigen，CD47 Glycoprotein，IAP，Integrin-Associated Signal Transducer，Protein MER6，OA3，CD47 Antigen，Integrin-Associated Protein
최고 연구 개발 단계	Phase 3 Clinical

영어 이름	Cluster of differentiation 47
표적 별명	MER6，CD47，Leukocyte surface antigen CD47，CD47 Molecule，Antigenic Surface Determinant Protein OA3，CD47 Antigen (Rh-Related Antigen， Integrin-Associated Signal Transducer)，Antigen Identified By Monoclonal Antibody 1D8，Integrin Associated Protein，Rh-Related Antigen，CD47 Glycoprotein，IAP，Integrin-Associated Signal Transducer，Protein MER6，OA3，CD47 Antigen，Integrin-Associated Protein
시판 약물 수	0
임상 약물 수	48
최고 연구 개발 단계	Phase 3 Clinical

CD47 제품 목록

속성
Protein (21)Beads (1)Kits (2)
제품 라이브러리
온라인 (24)
종
Human (12)Mouse (5)Cynomolgus / Rhesus macaque (4)Rat (1)Rabbit (1)Canine (1)
태그
Fc Tag (5)His Tag (6)Fc Tag & Avi Tag (3)Mouse IgG Fc Tag (2)His Tag & Avi Tag (4)Mouse IgG Fc Tag & Avi Tag (1)- (3)
마커
Unconjugated (13)Biotin-labeled (7)FITC Labeled (1)- (3)

제품 번호	종	발현 시스템	제품 설명
HOT CD7-H5227	Human	HEK293	Human CD47 Protein, His Tag (MALS verified)
HOT CD7-H522a	Human	HEK293	Human CD47 Protein, His Tag, low endotoxin (MALS verified)
HOT CD7-H82E9	Human	HEK293	Biotinylated Human CD47 Protein, His,Avitag™ (MALS verified)
HOT CD7-M5251	Mouse	HEK293	Mouse CD47 Protein, Fc Tag (MALS verified)
HOT CD7-C52H1	Cynomolgus / Rhesus macaque	HEK293	Cynomolgus / Rhesus macaque CD47 Protein, His Tag, low endotoxin
CD7-H5256	Human	HEK293	Human CD47 Protein, Fc Tag, low endotoxin (MALS verified)
CD7-H52A5	Human	HEK293	Human CD47 Protein, Mouse IgG2a Fc Tag, low endotoxin
CD7-H82A3	Human	HEK293	Biotinylated Human CD47 Protein, Mouse IgG2a Fc,Avitag™ (MALS verified)
CD7-H82F6	Human	HEK293	Biotinylated Human CD47 Protein, Fc,Avitag™ (MALS verified)
CD7-HA2E9	Human	HEK293	Unconjugated Human CD47 Protein, His,Avitag™ (HPLC verified)

총 수량24

CD47분자 배경

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

CD47분자 별명

CD47,MER6,IAP,OA3

라이선싱 협력

프로젝트 이름	약물 유형	치료 영역	적응증	단계	권리 지역
CD47 Monoclonal Antibody	Monospecific antibody	Oncology/Cancer	Advanced solid tumor,Advanced hematological tumor	IND	Global

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
IMC-002(Immuneoncia)	IMC-002; 3D-197; 3D197	Phase 3 Clinical	Immuneoncia Therapeutics Inc	Hematologic Neoplasms; Lymphoma; Neoplasm Metastasis; Neoplasms; Neuromyelitis Optica; Solid tumours; Stomach Neoplasms	상세
Timdarpacept	IMM01; IMM 01; IMC-001	Phase 3 Clinical		Atherosclerosis; Cardiovascular Diseases; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Lymphoma; Lymphoma, Extranodal NK-T-Cell; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms; Solid tumours	상세
Evorpacept	ALX148; ALX-148	Phase 3 Clinical	Alexo Therapeutics	Carcinoma, Transitional Cell; Composite Lymphoma; Esophageal Neoplasms; Head and Neck Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Metastatic breast cancer; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasm Metastasis; Neoplasms; Oropharyngeal Neoplasms; Plasmablastic Lymphoma; Primary mediastinal B cell lymphoma; Richter's Syndrome; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Urinary Bladder Neoplasms	상세
Amulirafusp alfa	IMC-002; IMM-0306	Phase 3 Clinical		Glomerulonephritis, Membranous; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Nephrosis; Neuromyelitis Optica	상세
Ligufalimab	AK-117	Phase 3 Clinical		Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Esophageal Neoplasms; Hodgkin Disease; Leukemia, Myeloid, Acute; Lymphoma; Myelodysplastic Syndromes; Neoplasms; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms	상세
Magrolimab	5F9; Hu5F9-G4; ONO-7913; GS-4721	Phase 2 Clinical	Stanford University	Brain Neoplasms; Carcinoma, Transitional Cell; Colorectal Neoplasms; Hodgkin Disease; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Multiple Myeloma; Mycosis Fungoides; Myelodysplastic Syndromes; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Sezary Syndrome; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms	상세
AO-176	AO-176; Ti-104; Ti-108; Ti-176	Phase 2 Clinical	Arch Oncology Inc	Multiple Myeloma; Solid tumours	상세
Ontorpacept	TTI-621	Phase 2 Clinical	The Hospital For Sick Children, Trillium Therapeutics Inc, University Health Network (Uhn)	Breast Neoplasms; Carcinoma, Merkel Cell; Carcinoma, Squamous Cell; Hematologic Neoplasms; Leiomyosarcoma; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Melanoma; Multiple Myeloma; Mycosis Fungoides; Papillomavirus Infections; Primary mediastinal B cell lymphoma; Sarcoma; Skin Neoplasms; Solid tumours	상세
AUR-103	AUR-103	Phase 2 Clinical	Aurigene	Gastroesophageal Junction Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Solid tumours; Stomach Neoplasms	상세
Maplirpacept	TTI-622; PF-07901801	Phase 2 Clinical	Trillium Therapeutics Inc	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Hematologic Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Multiple Myeloma; Ovarian Neoplasms; Peritoneal Neoplasms; Primary mediastinal B cell lymphoma; Skin Neoplasms	상세
DSP-107	KAHR-107; DSP-107	Phase 2 Clinical	Kahr Medical	Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Solid tumours	상세
BRB-002	BRB-002	Phase 2 Clinical	Bitterroot Bio Inc	Atherosclerosis; Cardiovascular Diseases; Vasculitis	상세
HCB-101	HCB-101	Phase 2 Clinical	HanchorBio Inc	Carcinoma, Renal Cell; Colorectal Neoplasms; Lymphoma, Non-Hodgkin; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms	상세
LB-101 (Centessa Pharmaceuticals)	LB-101 (Centessa Pharmaceuticals); LB-101 Tetravalent PD-L1xCD47 LockBody bispecific monoclonal antibody	Phase 2 Clinical	Centessa Pharmaceuticals Plc	Solid tumours	상세
Spevatamig	PT-886; PT886	Phase 2 Clinical	Phanes Therapeutics Inc	Biliary Tract Neoplasms; Carcinoma, Pancreatic Ductal; Esophageal Neoplasms; Gastroesophageal Junction Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms	상세
Peluntamig	PT-217	Phase 2 Clinical	Phanes Therapeutics Inc	Carcinoma, Neuroendocrine; Neuroendocrine Carcinoma of Lung; Prostatic Neoplasms; Small Cell Lung Carcinoma; Solid tumours	상세
BCD-106	BCD-106	Phase 2 Clinical	BIOCAD JSC	Solid tumours	상세
BAT-7104	BAT-7104	Phase 2 Clinical	Bio-Thera Solutions Ltd	Neoplasms; Solid tumours	상세
IMM-2902	IMM-2902	Phase 2 Clinical		Breast Neoplasms; Cholangiocarcinoma; Lung Neoplasms; Solid tumours; Stomach Neoplasms	상세
6MW-3211	6MW3211; 6MW-3211	Phase 2 Clinical	Mabwell (Shanghai) Bioscience Co Ltd	Carcinoma, Renal Cell; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Myelodysplastic Syndromes; Neoplasms	상세
JMT-601	JMT-601	Phase 2 Clinical	Shanghai Jmt-Bio Inc	Glomerulonephritis, Membranous; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Nephrosis	상세
Lemzoparlimab	ABBV-IMAB-TJC4; TJ-1133; TJ-011133; TJC-4	Phase 2 Clinical	Abbvie Inc, I-Mab Biopharma Co Ltd	Hematologic Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Solid tumours	상세
Anti-CD47 monoclonal antibody (Biocad)		Phase 1 Clinical	BIOCAD JSC	Neoplasms	상세
Recombinant humanized monoclonal antibody MIL95 (Mabworks/Connaught Biomedical Technology)	MIL-95; CM-312	Phase 1 Clinical	Beijing Mabworks Biotech Co Ltd	Leukemia, Myeloid, Acute; Lymphoma; Neoplasms; Solid tumours	상세
Zeripatamig	TG-1801; NI-1701	Phase 1 Clinical	Novimmune Sa	Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Richter's Syndrome	상세
SL-172154	SL-172154; SIRPα -Fc-CD40L	Phase 1 Clinical	Shattuck Labs Inc	Carcinoma, Ovarian Epithelial; Carcinoma, Squamous Cell; Fallopian Tube Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Ovarian Neoplasms; Peritoneal Neoplasms; Squamous Cell Carcinoma of Head and Neck	상세
Simridarlimab	IBI-322; IBI322	Phase 1 Clinical		Bone Marrow Neoplasms; Hematologic Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, T-Cell; Neoplasms; Solid tumours	상세
anti-CD47 mAb (Hangzhou Sumgen Biotechnology/Zhongsheng Sumgen Biotechnology)	SG-404 (Hangzhou Sumgen)	Phase 1 Clinical	Zhongsheng Shangjian Biological Medicine (Hangzhou) Co Ltd	Hematologic Neoplasms; Solid tumours	상세
anti-CD47/CD20 bispecific antibody (Bristol-Myers Squibb Co)		Phase 1 Clinical	Bristol-Myers Squibb Company	Hematologic Neoplasms; Lymphoma, Non-Hodgkin	상세
ZL-1201	ZL-1201	Phase 1 Clinical	Zai Lab (Shanghai) Co Ltd	Hematologic Neoplasms; Neoplasms; Solid tumours	상세
HMPL-A83	HMPL-A-83; HMPL-A83	Phase 1 Clinical		Hematologic Neoplasms; Neoplasms; Solid tumours	상세
NI-1801	NI-1801	Phase 1 Clinical	Light Chain Bioscience Ltd	Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Pancreatic Ductal; Solid tumours; Triple Negative Breast Neoplasms	상세
IMM-0306S	IMM0306S; IMM-0306S	Phase 1 Clinical		Lupus Erythematosus, Systemic	상세
AK-132	AK132; AK-132	Phase 1 Clinical		Neoplasms; Solid tumours	상세
D3L-001	D3L-001	Phase 1 Clinical	D3 Bio (Wuxi) Co Ltd	Neoplasms; Solid tumours	상세
FP-002 (Fapon Biopharma)	FP-002	Phase 1 Clinical	Guangdong Fapon Biopharma Inc	Neoplasms; Solid tumours	상세
BC-007 (Dragonboat Biopharmaceutical)	BC-007	Phase 1 Clinical	Dragonboat Biopharmaceutical	Neoplasms; Solid tumours	상세
SG-1906	SG-1906; SG1906	Phase 1 Clinical	Hangzhou Shangjian Biotechnology Co Ltd	Neoplasms; Solid tumours	상세
LD-002	LD-002	Phase 1 Clinical	Zhejiang Blue Shield Pharmaceutical Co Ltd	Hematologic Neoplasms; Lymphoma, Non-Hodgkin; Solid tumours	상세
SHS-009	SHS-009; SH009; SH-009	Phase 1 Clinical	Nanjing Sanhome Pharmaceutical Co Ltd	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Liver Neoplasms; Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms	상세
Monoclonal Antibody (Mab) sB24M		Phase 1 Clinical	Swiss Biopharma Med GmbH	Pyoderma; Pyoderma Gangrenosum	상세
IMM-2520	IMM-2520	Phase 1 Clinical		Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck	상세
STI-6643	STI-6643	Phase 1 Clinical	Sorrento Therapeutics Inc	Neoplasms; Solid tumours	상세
PF-07257876		Phase 1 Clinical	Pfizer Inc	Carcinoma, Non-Small-Cell Lung; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck	상세
TQB-2928	TQB-2928	Phase 1 Clinical	Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd	Carcinoma, Non-Small-Cell Lung; Hematologic Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasms; Osteosarcoma; Solid tumours	상세
IMM2505	IMM2505; IMM-2505	Phase 1 Clinical	SunHo (China) BioPharmaceutical Co Ltd	Solid tumours	상세
SG404	SG-404; SG404	Phase 1 Clinical	Hangzhou Shangjian Biotechnology Co Ltd	Neoplasms	상세
Kintuzumab(GenSci)		Phase 1 Clinical	Changchun GeneScience Pharmaceuticals Co Ltd	Hematologic Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Solid tumours	상세

제품 리뷰

L***z2026-02-12
0사람들이 좋아합니다
Mouse CD47 Protein, His Tag, low endotoxin (MALS verified)
I have been using the protein for ELISA assays, andit has met our experimental requirements without any issues. Low doses are sufficient for coating, which makes the assays cost-effective while still providing strong and consistent signal. The shipping was fast and the product arrived in excellent condition.
A***r2023-01-31
0사람들이 좋아합니다
Human CD47 Protein, His Tag (MALS verified)
A new ELISA binding was set up with this new recombinant protein. Among the various suppliers evaluated, the one from Acro Biosystem has been selected. Low doses are needed for coating in comparison to other providers. In addition, data quality was confirmed on repeatition runs. Finally, product delivery was quick and the interaction with our local business development manager is highly satisfaying.
R***e2022-09-10
0사람들이 좋아합니다
Human CD47 Protein, Fc Tag, low endotoxin (MALS verified)
Heard about ACRO from word of mouth from coworkers here at PPD and decided to browse the internet . My team purchased this product for some ELISA testing at the lab. We have been satisfied with the results so far. Great repeatability, sustainability, and specificity as compared to other vendors! It’s very creditable in my opinion. All and all ACRO definitely has some great quality products that are also more cost-effective compared to different vendors like MSD!