언어 선택

CD4

CD4 분자 정보

영어 이름	T-cell surface antigen CD4	시판 약물 수	1
임상 약물 수	25	표적 별명	CD4mut，CD4 Antigens，T-cell surface antigen T4/Leu-3，T-cell surface glycoprotein CD4，CD4，CD4 Molecule，CD4 Antigen (P55)，CD4 Receptor，CD4 Antigen
최고 연구 개발 단계	Approved

영어 이름	T-cell surface antigen CD4
표적 별명	CD4mut，CD4 Antigens，T-cell surface antigen T4/Leu-3，T-cell surface glycoprotein CD4，CD4，CD4 Molecule，CD4 Antigen (P55)，CD4 Receptor，CD4 Antigen
시판 약물 수	1
임상 약물 수	25
최고 연구 개발 단계	Approved

CD4 제품 목록

속성
Protein (15)Antibody (2)Cell Grade Beads (1)
제품 라이브러리
온라인 (18)
종
Human (13)Rhesus macaque (3)Rabbit (1)Mouse (1)
태그
Fc Tag (3)His Tag (9)Fc Tag & Avi Tag (1)His Tag & Avi Tag (2)- (3)
마커
Unconjugated (5)Biotin-labeled (3)FITC Labeled (2)PE Labeled (2)APC Labeled (1)PE-CY7 Labeled (1)AF488 Labeled (2)AF647 Labeled (1)- (1)

제품 번호	종	발현 시스템	제품 설명
HOT CD4-H82E8	Human	HEK293	Biotinylated Human CD4 Protein, His,Avitag™ (MALS verified)
HOT CD4-HA2H9	Human	HEK293	APC-Labeled Human CD4 Protein, His TagStar Staining
HOT CD4-HF255	Human	HEK293	FITC-Labeled Human CD4 Protein, Fc Tag
HOT CD4-HP2E3	Human	HEK293	PE-Labeled Human CD4 Protein, His Tag (Site-specific conjugation)
HOT LE3-H5228	Human	HEK293	Human CD4 / LEU3 Protein, His Tag (MALS verified)
CD4-H5259	Human	HEK293	Human CD4 Protein, Fc Tag (MALS verified)
CD4-H82F3	Human	HEK293	Biotinylated Human CD4 Protein, Fc,Avitag™ (MALS verified)
CD4-HA225	Human	HEK293	Alexa Fluor™ 488-Labeled Human CD4 Protein, His Tag
CD4-HA2H7	Human	HEK293	Alexa Fluor™ 488-Labeled Human CD4 Protein, His TagStar Staining
CD4-HA2H8	Human	HEK293	Alexa Fluor™ 647-Labeled Human CD4 Protein, His TagStar Staining

총 수량18

CD4분자 배경

T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

CD4분자 별명

CD4,CD4mut,LEU3

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Semzuvolimab	dB4; UB-421; mAb-B4	Phase 3 Clinical	United Biomedical Inc	HIV Infections	상세
ITV 1(Nonindustrial source)	ITV-1	Phase 3 Clinical	Immunotech Laboratories, Synexa Life Sciences	HIV Infections	상세
RB-0003	RB-0003; BNT-111	Phase 2 Clinical	Biontech Se, Tron	Melanoma	상세
VRC-01-LS	VRC-HIVMAB-080-00-AB; VRC-01-LS	Phase 2 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	HIV Infections	상세
VRC-07-523	VRC-07-523-L S; VRC-HIVMAB075-00-AB; VRC-HIVMAB-075 -00-AB; VRC-07-523; TMB-380	Phase 2 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid), Taimed Biologics Inc	Acquired Immunodeficiency Syndrome; HIV Infections; Sexually Transmitted Diseases, Viral	상세
GEN-009	GEN-009	Phase 2 Clinical	Genocea Biosciences Inc	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Skin Melanoma; Squamous Cell Carcinoma of Head and Neck	상세
Tregalizumab	hB-F5; BT-061	Phase 2 Clinical	Biotest Pharma Gmbh	Arthritis, Rheumatoid; Asthma; Drug Hypersensitivity; Psoriasis	상세
Lotivibart	VH-3810109; GSK-3810109-A; VH-109; N6LS; Z258‐N6LS; VRC-HIVMAB091-00-AB; GSK-3810109	Phase 2 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	HIV Infections	상세
MR-001	MR001; MR-001	Phase 2 Clinical	Shenzhen Maijiarui Biotechnology Co Ltd	Carcinoma, Pancreatic Ductal; Pancreatic Neoplasms; Solid tumours; Triple Negative Breast Neoplasms	상세
IMCY-0141	IMCY-0141	Phase 2 Clinical	Imcyse Sa	Multiple Sclerosis, Relapsing-Remitting	상세
Autologous Regulatory Т-cell Therapy		Phase 2 Clinical	Institute Of Biophysics And Cell Engineering Of National Academy Of Sciences Of Belarus	Scleroderma, Systemic	상세
TMB-365	TMB-365	Phase 2 Clinical	Taimed Biologics Inc	HIV Infections	상세
CD4-directed chimeric antigen receptor engineered T-cells (Icell Gene)	CD4CAR (Icell Gene)	Phase 1 Clinical	Icell Gene Therapeutics (Int'L) Ltd, Stony Brook University School Of Medicine, University Of Louisville	Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, T-Cell; Lymphoma, T-Cell	상세
T-allo-10	T-allo-10	Phase 1 Clinical	Stanford University	Graft vs Host Disease; Hematologic Diseases; Hodgkin Disease; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	상세
Anti-CD4 CAR T-cell therapy (University of Pennsylvania)	CAR-C34ZFN	Phase 1 Clinical	University Of Pennsylvania	HIV Infections	상세
10E8.4/iMab (Aaron Diamond AIDS Research Center)	TMB-370	Phase 1 Clinical	Aaron Diamond Aids Research Center For The City Of New York, Inc	HIV Infections	상세
CD4CAR	ICG-122; CD4CAR	Phase 1 Clinical	iCell Gene Therapeutics LLC	Leukemia, Myelomonocytic, Chronic; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Multiple Myeloma; Mycosis Fungoides; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	상세
MazF gene therapy (Takara Bio)		Phase 1 Clinical	Takara Bio Inc	HIV Infections	상세
CALRLong36 peptide (Herlev Hospital)		Phase 1 Clinical	Herlev Hospital	Myeloproliferative Disorders	상세
VRC-HIVMAB060-00-AB	VRC-HIVMAB060-00-AB; VRC01	Phase 1 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	HIV Infections	상세
VRC-HIVMAB0115-00-AB		Phase 1 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	HIV Infections	상세
LM-49		Phase 1 Clinical	Shanxi Medical University, Shanxi University Of Traditional Chinese Medicine	Diabetic Nephropathies	상세
SCRI-E2CAR_EGFRtv1	SCRI-E2CAR_EGFRtv1	Phase 1 Clinical	Umoja BioPharma Inc	Osteosarcoma	상세
LB-1901	LB1901; LB-1901	Phase 1 Clinical		Leukemia, T-Cell; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral	상세
IT-1208 (Kyowa Hakko Kirin)	IT-1208	Phase 1 Clinical	Kyowa Hakko Kirin Co Ltd	Neoplasms	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Ibalizumab	Hu5A8; TMB-355; TNX-355; 5AB	Approved	Biogen Inc	特罗格佐, Trogarzo	United States	HIV Infections	Theratechnologies Inc	2018-03-06	HIV Infections	상세