언어 선택

CD38

CD38 분자 정보

영어 이름	Lymphocyte differentiation antigen CD38	시판 약물 수	3
임상 약물 수	48	표적 별명	EC:3.2.2.6，EC:2.4.99.20，2-Phospho-Cyclic-ADP-Ribose Transferase，Cyclic ADP-Ribose Hydrolase 1，2-Phospho-ADP-Ribosyl Cyclase，NAD(+) Nucleosidase，CD38 Antigen (P45)，2-Phospho-ADP-Ribosyl Cyclase/2-Phospho-Cyclic-ADP-Ribose Transferase，Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase，ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1，Cluster Of Differentiation 38，CD38 Antigen，EC 2.4.99.20，EC 3.2.2.6，ADPRC1，T10，2'-phospho-ADP-ribosyl cyclase，ADPRC 1，cADPr hydrolase 1，ADP-ribosyl cyclase 1，2'-phospho-cyclic-ADP-ribose transferase，CD38，CD38 Molecule，2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
최고 연구 개발 단계	Approved

영어 이름	Lymphocyte differentiation antigen CD38
표적 별명	EC:3.2.2.6，EC:2.4.99.20，2-Phospho-Cyclic-ADP-Ribose Transferase，Cyclic ADP-Ribose Hydrolase 1，2-Phospho-ADP-Ribosyl Cyclase，NAD(+) Nucleosidase，CD38 Antigen (P45)，2-Phospho-ADP-Ribosyl Cyclase/2-Phospho-Cyclic-ADP-Ribose Transferase，Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase，ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1，Cluster Of Differentiation 38，CD38 Antigen，EC 2.4.99.20，EC 3.2.2.6，ADPRC1，T10，2'-phospho-ADP-ribosyl cyclase，ADPRC 1，cADPr hydrolase 1，ADP-ribosyl cyclase 1，2'-phospho-cyclic-ADP-ribose transferase，CD38，CD38 Molecule，2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
시판 약물 수	3
임상 약물 수	48
최고 연구 개발 단계	Approved

CD38 제품 목록

속성
Protein (10)Beads (1)Antibody (1)Kits (1)
제품 라이브러리
온라인 (13)
종
Human (10)Cynomolgus (1)Mouse (1)Rabbit (1)
태그
His Tag (4)His Tag & Avi Tag (1)Fc Tag (2)Mouse IgG Fc Tag (1)- (3)Fc Tag & Avi Tag (1)Avi Tag (1)
마커
Unconjugated (6)Biotin-labeled (3)- (2)FITC Labeled (2)

제품 번호	종	발현 시스템	제품 설명
HOT CD8-H5224	Human	HEK293	Human CD38 Protein, His Tag (MALS verified)
HOT CD8-H5255	Human	HEK293	Human CD38 Protein, Fc Tag (MALS verified)
HOT CD8-H82E7	Human	HEK293	Biotinylated Human CD38 Protein, Avitag™,His Tag (MALS verified)
HOT CD8-HF2H5	Human	HEK293	FITC-Labeled Human CD38 Protein, His Tag (MALS verified)
CD8-H5253	Human	HEK293	Human CD38 Protein, Mouse IgG2a Fc Tag, low endotoxin
CD8-H8214	Human	HEK293	Biotinylated Human CD38 Protein, Avitag™
CD8-H82F5	Human	HEK293	Biotinylated Human CD38 Protein, Fc,Avitag™ (MALS verified)
CD8-HF255	Human	HEK293	FITC-Labeled Human CD38 Protein, Fc Tag
CEA-B039	Human	-	Human Soluble CD38 ELISA Kit
MBC-K010	Human	-	Human CD38-coupled Magnetic Beads

총 수량13

CD38분자 배경

CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.

CD38분자 별명

CD38,T10,cADPr hydrolase 1

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Mezagitamab	TAK-079	Phase 3 Clinical	Takeda Pharmaceutical Co Ltd	Autoimmune Diseases; Glomerulonephritis; Glomerulonephritis, IGA; Kidney Diseases; Lupus Erythematosus, Systemic; Multiple Myeloma; Myasthenia Gravis; Nephrosis; Purpura, Thrombocytopenic, Idiopathic; Thrombocytopenia	상세
Daratumumab biosimilar (Celltrion)	CT-P44	Phase 3 Clinical	Celltrion Inc	Multiple Myeloma	상세
Daratumumab biosimilar (Biocad)	BCD-264	Phase 3 Clinical	BIOCAD JSC	Multiple Myeloma	상세
SCTC-21-C	SCTC21C; SCTC-21-C; SCT-C21C	Phase 3 Clinical	SinoCelltech Ltd	Amyloidosis; Autoimmune Diseases; Glomerulonephritis, IGA; Hematologic Neoplasms; Immunoglobulin Light-chain Amyloidosis; Lupus Erythematosus, Systemic; Multiple Myeloma	상세
Daratumumab biosimilar (Henlius)	HLX-15	Phase 3 Clinical		Multiple Myeloma	상세
Recombinant anti-CD38 fully human monoclonal antibody (Henlius Biotech)		Phase 3 Clinical		Amyloidosis; Multiple Myeloma	상세
Recombinant human anti-CD38 momoclonal antibody(Sumgen)	SG-301; SG301	Phase 3 Clinical	Hangzhou Shangjian Biotechnology Co Ltd	Hematologic Neoplasms; Lupus Erythematosus, Systemic; Multiple Myeloma; Nephrotic Syndrome	상세
STI-6129	STI-6129; LNDS-1001	Phase 2 Clinical	Sorrento Therapeutics Inc	Immunoglobulin Light-chain Amyloidosis; Leukemia, Myeloid, Acute; Multiple Myeloma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Solid tumours	상세
Modakafusp alfa	TEV-48573; TAK-573	Phase 2 Clinical	Takeda Pharmaceutical Co Ltd	Melanoma; Multiple Myeloma; Neoplasms	상세
CLL1/CD33/CD38/CD7 CAR-T cell therapy		Phase 2 Clinical	Guangzhou Bio-Gene Technology Co Ltd	Leukemia, Myeloid, Acute	상세
Anti-CD38 Monoclonal Antibody (Genrix)		Phase 2 Clinical	Genrix (Shanghai) Biopharmaceutical Co Ltd	Multiple Myeloma	상세
4SCAR-T cell therapy (Shenzhen Geno-Immune Medical Institute)	4SCAR-T	Phase 2 Clinical	Shenzhen Geno-Immune Medical Institute	Autoimmune Diseases; Hematologic Neoplasms; Neuroblastoma	상세
REGN-7945	REGN7945; REGN-7945	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Multiple Myeloma	상세
Anti-CD38 Antibody(Institute of Hematology & Blood Diseases Hospital)		Phase 2 Clinical	Institute Of Hematology & Blood Diseases Hospital	Antiphospholipid Syndrome; Purpura, Thrombocytopenic, Idiopathic; Thrombocytopenia	상세
CID-103	TSK011010; CID-103	Phase 2 Clinical	Tusk Therapeutics Ltd	Multiple Myeloma; Purpura, Thrombocytopenic, Idiopathic; Rejection of renal transplantation; Thrombocytopenia	상세
BHV-1100	KP-1237; BHV-1100	Phase 2 Clinical	Biohaven Pharmaceuticals Inc, Kleo Pharmaceuticals, PeptiDream Inc	Multiple Myeloma	상세
Lumrotatug	CM-313	Phase 2 Clinical	Keymed Biosciences Co Ltd	Anemia; Anemia, Aplastic; Blood Platelet Disorders; Glomerulonephritis, IGA; Hematologic Neoplasms; Lupus Erythematosus, Systemic; Lymphoma; Multiple Myeloma; Purpura, Thrombocytopenic, Idiopathic; Thrombocytopenia	상세
89Zr-DFO-daratumumab		Phase 2 Clinical	Memorial Sloan Kettering Cancer Center	Multiple Myeloma	상세
64Cu-DOTA-daratumumab		Phase 1 Clinical	City Of Hope National Medical Center	Multiple Myeloma	상세
SAR-442257	SAR-442257	Phase 1 Clinical	Sanofi	Neoplasms	상세
Anti-BCMA anti-CD38 bispecific chimeric antigen receptor T cell therapy (Shengyan Pharmaceutical Technology)		Phase 1 Clinical	Shengyan Pharmaceutical Technology	Multiple Myeloma	상세
dual anti-BCMA/anti-CD38 CAR T-cell therapy (Shengyan Pharmaceutical Technology/Tongji Medical College)		Phase 1 Clinical	Tongji Medical College	Multiple Myeloma	상세
CD38 CAR T-cells		Phase 1 Clinical	Zhejiang University	Hematologic Neoplasms; Leukemia, Myeloid, Acute	상세
anti-CD38 CAR T-cell therapy (Shanghai Unicar-Therapy Bio-Medicine Technology/Soochow University/East China Normal University)		Phase 1 Clinical	Soochow University	Leukemia, Myeloid, Acute	상세
actinium-225 labeled daratumumab (Actinium Pharmaceuticals)		Phase 1 Clinical	Actinium Pharmaceuticals Inc, City Of Hope National Medical Center, National Cancer Institute	Hematologic Neoplasms; Multiple Myeloma	상세
T-007 (TNK Therapeutics/Celularity)		Phase 1 Clinical	Tnk Therapeutics Inc	Multiple Myeloma	상세
Anti-CD38 chimeric antigen receptor T cell therapy(Yake Biotechnology)	CAR-T CD-38	Phase 1 Clinical	Shanghai YaKe Biotechnology Co Ltd	Leukemia, Myeloid, Acute; Multiple Myeloma	상세
Indium In 111-DOTA-Daratumumab		Phase 1 Clinical	City Of Hope National Medical Center	Leukemia, Myeloid, Acute; Multiple Myeloma; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	상세
Daratumumab biosimilar (Jushi Biopharma)		Phase 1 Clinical	Jushi Biopharmaceutical Co Ltd	Multiple Myeloma	상세
CD38\CS1 Chimeric Antigen Receptor T Cells therapy(The Second Hospital Of Shandong University)		Phase 1 Clinical	The Second Hospital Of Shandong University	Multiple Myeloma	상세
SAR-444559	SAR444559; SAR-444559	Phase 1 Clinical	Sanofi	Inflammation	상세
68Ga-NB-381	68Ga-NB381; 68Ga-NB-381; 18F-FDG(The First Affiliated Hospital Of Beijing University)	Phase 1 Clinical	The First Affiliated Hospital Of Beijing University	Multiple Myeloma	상세
Dual CLL1/CD38 targeting CAR-T cell therapy (Gracell Biotechnologies)		Phase 1 Clinical	Gracell Biotechnologies (Shanghai) Co Ltd	Leukemia, Myeloid, Acute	상세
Universal CAR-T Cells therapy(Shenzhen Geno-Immune Medical Institute)		Phase 1 Clinical	Shenzhen Geno-Immune Medical Institute	Leukemia, Myeloid, Acute	상세
RB-0021	RB0021; RB-0021	Phase 1 Clinical	Ruiyang (Suzhou) Biological Technology Co Ltd	Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Myeloma	상세
KJ-C2320	KJ-C2320	Phase 1 Clinical	CARsgen Therapeutics Holdings Ltd	Leukemia, Myeloid, Acute	상세
Daratumumab biosimilar (Hangzhou Jiuyuan Gene Engineering)	JY43; JY-43	Phase 1 Clinical	Hangzhou Jiuyuan Gene Biomedical Co Ltd	Multiple Myeloma	상세
KYS202002A	KYS-202002A; KYS202002A	Phase 1 Clinical	Jiangsu Kanion Pharmaceutical Co Ltd	Lupus Erythematosus, Systemic; Multiple Myeloma	상세
ISB-2001	ISB-2001; ABBV-2001	Phase 1 Clinical	Ichnos Sciences Sa	Multiple Myeloma	상세
TNB-738	TNB-738	Phase 1 Clinical	TeneoFour Inc		상세
GBR-1342	GBR-1342; ISB-1342	Phase 1 Clinical	Glenmark Pharmaceuticals Ltd	Multiple Myeloma	상세
XmAb-968	XmAb968	Phase 1 Clinical	Xencor Inc	Hematologic Neoplasms; Leukemia, Promyelocytic, Acute	상세
XmAb-18968	XmAb-18968	Phase 1 Clinical	The Medical College Of Wisconsin Nonprofit	Leukemia, Myeloid, Acute	상세
211At-OKT10-B10		Phase 1 Clinical	Fred Hutchinson Cancer Research Center	Multiple Myeloma	상세
Y-150(Wuhan Yzy Biopharma/CSPC Pharmaceutical)	Y-150; Y150	Phase 1 Clinical	CSPC Pharmaceutical Group Ltd, Wuhan Yzy Biopharma Co Ltd	Multiple Myeloma	상세
Anti CD38 chimeric antigen receptor T-cell therapy (Sorrento Therapeutics)		Phase 1 Clinical	Celularity Inc, Sorrento Therapeutics Inc	Multiple Myeloma	상세
SAR-442085	SAR-442085	Phase 1 Clinical	Sanofi	Multiple Myeloma	상세
111Indium labeled daratumumab			City Of Hope National Medical Center, National Cancer Institute		상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Daratumumab/Hyaluronidase-fihj	DARA-PH20	Approved	Johnson & Johnson Innovative Medicine	Darzalex Faspro, Darzquro, DARZALEX FASPRO, DARZALEX-SC	United States	Multiple Myeloma	Janssen Biotech Inc	2020-05-01	Amyloidosis; Anemia, Aplastic; Bone marrow transplant rejection; Hematologic Neoplasms; Hodgkin Disease; Immunoglobulin Light-chain Amyloidosis; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Monoclonal Gammopathy of Undetermined Significance; Multiple Myeloma; Myelodysplastic Syndromes; Peripheral Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Rejection in heart transplantation; Smoldering Multiple Myeloma	상세
Isatuximab	SAR-650984; hu38SB19	Approved	Immunogen Inc	Sarclisa	United States	Multiple Myeloma	Sanofi-Aventis U.S. Llc	2020-03-02	Amyloidosis; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Carcinoma, Non-Small-Cell Lung; Constipation; Diarrhea; Gastrointestinal Hemorrhage; Goiter, Nodular; Hematologic Neoplasms; Hepatomegaly; Hodgkin Disease; Immunoglobulin Light-chain Amyloidosis; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Leukemia, T-Cell; Lymphadenopathy; Lymphoma; Lymphoma, Non-Hodgkin; Macroglossia; Multiple Myeloma; Nausea; Neoplasms; Paraproteinemias; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Purpura; Satiety Response; Smoldering Multiple Myeloma	상세
Daratumumab	JNJ-54767414	Approved	Johnson & Johnson Innovative Medicine	Darzalex, 兆珂, 兆珂速	United States	Multiple Myeloma	Janssen Biotech Inc	2015-11-16	Alzheimer Disease; Amyloidosis; Anemia, Aplastic; Autoimmune Diseases; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Genital Neoplasms, Male; Glioblastoma; Glomerulonephritis; Hemangioma, Cavernous, Central Nervous System; Hodgkin Disease; Hypersensitivity; Immunoglobulin Light-chain Amyloidosis; Kidney Neoplasms; Leukemia, Myeloid, Acute; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, Extranodal NK-T-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, Primary Effusion; Multiple Myeloma; Myelodysplastic Syndromes; Paraproteinemias; POEMS Syndrome; Prostatic Neoplasms; Purpura, Thrombocytopenic, Idiopathic; Rejection of renal transplantation; Rejection of organ transplantation; Renal Insufficiency; Skin Diseases; Smoldering Multiple Myeloma; Stevens-Johnson Syndrome; Urologic Neoplasms; Waldenstrom Macroglobulinemia	상세

제품 리뷰

Y***u2023-03-31
0사람들이 좋아합니다
Biotinylated Human CD38 Protein, Avitag™,His Tag (MALS verified)
This product can be used at < 0.4 ug/ml as a detection agent to quantify anti CD38 antibodies in a binding assay. Anti CD38 antibodies in either bovine serum albumin based sample diluent or murine serum can be detected by this production without a problem. Specific signals from the subsequent streptavidin conjugated enzyme reaction were very strong and very low noise from the negative control antibody group.
Y***u2023-03-16
0사람들이 좋아합니다
Mouse CD38 Protein, His Tag (MALS verified)
Used 3 ug/ml of this protein as the capture antigen in an ELISA assay to screen for anti-mouse CD38 mAbs. Very strong signal from the positive control anti-mouse CD38 mAb (clone: NIMR5) and no binding to several anti-human CD38 mAbs or the anti-IgG secondary Ab in the assay. The "ETD of in-stock products: 2 business days" statement on Acro website was accurate. Fast shipment. Professional COA and instructions on how to reconstitute and store this product.
1***02019-10-11
0사람들이 좋아합니다
Human CD38 Protein, His Tag (MALS verified)
I bought a lot of products. This protein has high purity and good bioactivity. Whether it is for ELISA or functional assay, all went smoothly. The price is favorable and the service is also good. I support and recommend ACRO! Go ACRO!