언어 선택

CD30

CD30 분자 정보

영어 이름	Tumor necrosis factor receptor superfamily member 8	시판 약물 수	1
임상 약물 수	25	표적 별명	CD30，CD30L receptor，TNFRSF8，Lymphocyte activation antigen CD30，TNF Receptor Superfamily Member 8，D1S166E，Tumor Necrosis Factor Receptor Superfamily， Member 8，Cytokine Receptor CD30，CD30 Antigen，Ki-1，Ki-1 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 8
최고 연구 개발 단계	Approved

영어 이름	Tumor necrosis factor receptor superfamily member 8
표적 별명	CD30，CD30L receptor，TNFRSF8，Lymphocyte activation antigen CD30，TNF Receptor Superfamily Member 8，D1S166E，Tumor Necrosis Factor Receptor Superfamily， Member 8，Cytokine Receptor CD30，CD30 Antigen，Ki-1，Ki-1 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 8
시판 약물 수	1
임상 약물 수	25
최고 연구 개발 단계	Approved

CD30 제품 목록

속성
Protein (11)
제품 라이브러리
온라인 (11)
종
Human (10)Mouse (1)
태그
Fc Tag (3)His Tag & Avi Tag (1)Llama IgG Fc Tag (1)His Tag (5)Fc Tag & Avi Tag (1)
마커
Unconjugated (4)Biotin-labeled (2)FITC Labeled (2)PE Labeled (1)AF488 Labeled (1)AF647 Labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT CD0-H52H5	Human	HEK293	Human CD30 / TNFRSF8 Protein, His Tag, low endotoxin
HOT CD0-H82E6	Human	HEK293	Biotinylated Human CD30 / TNFRSF8 Protein, Avitag™,His Tag (MALS verified)
HOT CD0-HP2E3	Human	HEK293	PE-Labeled Human CD30 / TNFRSF8 Protein, His Tag (Site-specific conjugation)
CD0-H5250	Human	HEK293	Human CD30 / TNFRSF8 Protein, Fc Tag (MALS verified)
CD0-H82F4	Human	HEK293	Biotinylated Human CD30 / TNFRSF8 Protein, Fc,Avitag™ (MALS verified)
CD0-HA2H7	Human	HEK293	Alexa Fluor™ 488-Labeled Human CD30 / TNFRSF8 Protein, His Tag (HPLC verified)
CD0-HA2H9	Human	HEK293	Alexa Fluor™ 647-Labeled Human CD30 / TNFRSF8 Protein, His Tag
CD0-HF250	Human	HEK293	FITC-Labeled Human CD30 / TNFRSF8 Protein, Fc Tag
CD0-HF2H4	Human	HEK293	FITC-Labeled Human CD30 / TNFRSF8 Protein, His Tag
TN8-H5250	Human	HEK293	Human CD30 / TNFRSF8 Protein, Llama IgG2b Fc Tag, low endotoxin

총 수량11

CD30분자 배경

Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

CD30분자 별명

TNFRSF8,CD30,D1S166E,Ki-1

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Acimtamig	AFM-13	Phase 2 Clinical	The University Of Texas MD Anderson Cancer Center	Hodgkin Disease; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mycosis Fungoides	상세
ATLCAR.CD30 cells (UNC Lineberger Comprehensive Cancer Center)		Phase 2 Clinical	Unc Lineberger Comprehensive Cancer Center	Hodgkin Disease; Immune System Diseases; Immunoproliferative Disorders; Lymphatic Diseases; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Lymphomatoid Papulosis; Lymphoproliferative Disorders; Mycosis Fungoides; Neoplasms; Neoplasms, Germ Cell and Embryonal; Sezary Syndrome	상세
Autologous CD30+ CAR T Cells therapy(New York Medical College)		Phase 2 Clinical	New York Medical College, University Of North Carolina At Chapel Hill	Hodgkin Disease	상세
Itezocabtagene autoleucel	TT-11; TT11	Phase 2 Clinical	Tessa Therapeutics Ltd	Hodgkin Disease; Lymphoma, Extranodal NK-T-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Primary mediastinal B cell lymphoma	상세
BRD-01	BRD-01	Phase 2 Clinical	Wuhan BioRaid Biotechnology Co Ltd	Hematologic Neoplasms; Hodgkin Disease	상세
PRA-052	PRA-052; MK-8690; PR-600	Phase 2 Clinical	Prometheus Biosciences Inc	Colitis, Ulcerative	상세
HSP-CAR-30	HSP-CAR-30	Phase 2 Clinical	Fundació Institut De Recerca De L	Hodgkin Disease; Lymphoma, T-Cell	상세
Anti-CD30 CAR T-cell therapy (General Hospital of the People's Liberation Army/Cellular Biomedicine)	CAR30-NKT; CBM-C30.1; CD30ScFv-CD8-CD137-CD3zeta	Phase 2 Clinical	Pla General Hospital	Hodgkin Disease	상세
Anti-CD30 chimeric antigen receptor T cell therapy (Immune cell)		Phase 1 Clinical	Immune Cell Inc	Hodgkin Disease; Lymphoma, Large-Cell, Anaplastic	상세
CD30.CAR-EBVST cell therapy (Baylor College of Medicine)	TT-11X	Phase 1 Clinical	Baylor College Of Medicine, Tessa Therapeutics Ltd	Hodgkin Disease; Lymphoma, Extranodal NK-T-Cell; Lymphoma, Large B-Cell, Diffuse	상세
EBV-specific-CAR.CD30	EBV-specific-CAR.CD30; CAR.CD30 EBV-specific-CTLs	Phase 1 Clinical	Baylor College Of Medicine, Methodist Hospital System, Texas Children'S Hospital	Hodgkin Disease; Lymphoma, Non-Hodgkin	상세
Anti-CD30 CAR T-cell therapy (Wuhan Bio-Raid)		Phase 1 Clinical	Wuhan BioRaid Biotechnology Co Ltd	Angioimmunoblastic T-cell Lymphoma; Hematologic Neoplasms; Hodgkin Disease; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, Extranodal NK-T-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral	상세
B-0069 (Shanghai Pharmaceuticals Holding)	F0002-ADC; B-006(SCP)	Phase 1 Clinical	Shanghai Pharmaceuticals Holding Co Ltd	Hematologic Neoplasms; Hodgkin Disease; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral	상세
CD30.CAR	H-27721; CD30.CAR	Phase 1 Clinical	Baylor College Of Medicine	Hodgkin Disease; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral	상세
CD30 CAR-T Cells therapy (Unicar-Therapy Bio-Medicine Technology)	U29	Phase 1 Clinical	Shanghai Unicar-Therapy Bio-Medicine Technology Co Ltd	Lymphoma	상세
ATLCAR.CD30.CCR4		Phase 1 Clinical	Unc Lineberger Comprehensive Cancer Center	Immune System Diseases; Immunoproliferative Disorders; Lymphatic Diseases; Lymphoma; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Lymphoma, T-Cell, Cutaneous; Lymphomatoid Papulosis; Lymphoproliferative Disorders; Mycosis Fungoides; Neoplasms; Sezary Syndrome	상세
Chimeric antigen receptor gene modified T cells therapy (Qilu Cell Therapy Engineering&Technology)		Phase 1 Clinical	Shandong Qilu Cell Treapy Engineering&Technology Co Ltd	Lymphoma; Lymphoma, B-Cell; Lymphoma, T-Cell	상세
Anti-CD20/CD30-CAR-T Cell therapy(Shanghai Tongji Hospital)		Phase 1 Clinical	Shanghai Tongji Hospital	Leukemia, B-Cell; Lymphoma; Lymphoma, B-Cell	상세
CD30-Targeted LCAR-HL30 Cells therapy(Legend Biotechnology)		Phase 1 Clinical		Hodgkin Disease; Lymphoma, Large-Cell, Anaplastic	상세
SGN-35C	SGN-35C; PF-08046044	Phase 1 Clinical	Seagen Inc	Hodgkin Disease; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral	상세
Anti-CD30 CAR T-cell therapy		Phase 1 Clinical	Minghui (Nanjing) Gene Biotechnology Co Ltd	Hodgkin Disease; Lymphoma, Large-Cell, Anaplastic	상세
CD30 biAb-AATC(The Medical College Of Wisconsin Nonprofit)		Phase 1 Clinical	The Medical College Of Wisconsin Nonprofit	Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Cutaneous	상세
Anti-CD30 CAR-T cell therapy (National Cancer Institute)	Hu30-CD28z	Phase 1 Clinical	National Cancer Institute	Enteropathy-Associated T-Cell Lymphoma; Lymphoma; Lymphoma, Extranodal NK-T-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral	상세
SGN-CD30C	SGN-CD30C	Phase 1 Clinical	Seattle Genetics Inc	Lymphoma	상세
Anti-CD30 chimeric antigen receptor T cell therapy (Yake Biotechnology)		Clinical	Shanghai YaKe Biotechnology Co Ltd	Hodgkin Disease	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Brentuximab vedotin	cAC10-vcMMAE; SGN-30; cAC10-Val-Cit-MMAE; cAC-10; SGD-1010; SGN-35	Approved	Seagen Inc	Adcetris, 安适利	United States	Lymphoma, Large-Cell, Anaplastic; Hodgkin Disease	Seagen Inc	2011-08-19	Anemia, Refractory, with Excess of Blasts; Carcinoma; Enteropathy-Associated T-Cell Lymphoma; Graft vs Host Disease; Hematologic Diseases; Hematologic Neoplasms; Hidradenitis Suppurativa; HIV Infections; Hodgkin Disease; Leukemia, Mast-Cell; Leukemia, Myeloid, Acute; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Lymphomatoid Papulosis; Mastocytosis, Systemic; Mesothelioma; Mycosis Fungoides; Myelodysplastic Syndromes; Neoplasms; Neoplasms, Germ Cell and Embryonal; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Kaposi; Scleroderma, Diffuse; Scleroderma, Systemic; Sezary Syndrome; Solid tumours	상세

제품 리뷰

R*** 2021-09-22
3사람들이 좋아합니다
FITC-Labeled Human CD30 / TNFRSF8 Protein, His Tag
Our research group work with CAR-T therapy for the treatment of hematological malignancies, and use the Fitc-Labeled Human CD30 protein for detection of CAR30 cells in patients by flow cytometry. Our results are fantastic, because the observe consistency and a reproducible experiments by flow cytometry. The logistic speed is very effective and allows us to work always up to date with our projects.
1***22020-01-10
0사람들이 좋아합니다
Human CD30 / TNFRSF8 Protein, Fc Tag (MALS verified)
There are many CD30 products, with various tags. What I chose was the hFc tag protein. I also purchased CD30L for Fortebio experiment. The result was pretty good.