언어 선택

CD28

CD28 분자 정보

영어 이름	T-cell-specific surface glycoprotein CD28	시판 약물 수	0
임상 약물 수	32	표적 별명	CD28，CD28 Antigen，T-Cell-Specific Surface Glycoprotein CD28，CD28 Antigen (Tp44)，Tp44，CD28 Antigens，CD28 Molecule，T-Cell-Specific Surface Glycoprotein
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	T-cell-specific surface glycoprotein CD28
표적 별명	CD28，CD28 Antigen，T-Cell-Specific Surface Glycoprotein CD28，CD28 Antigen (Tp44)，Tp44，CD28 Antigens，CD28 Molecule，T-Cell-Specific Surface Glycoprotein
시판 약물 수	0
임상 약물 수	32
최고 연구 개발 단계	Phase 2 Clinical

CD28 제품 목록

속성
Protein (9)Antibody (6)Kits (1)
제품 라이브러리
온라인 (16)
종
Mouse (10)Human / Cynomolgus / Rhesus macaque (5)Rat (1)
태그
His Tag (3)Fc Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Fc Tag (2)His Tag & Avi Tag (2)- (7)
마커
Unconjugated (9)Biotin-labeled (4)- (1)PE Labeled (1)APC Labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT GMP-MC2824	Mouse	HEK293	GMP Monoclonal Anti-Human CD28 Antibody
HOT CD8-H52H3	Human / Cynomolgus / Rhesus macaque	HEK293	Human / Cynomolgus / Rhesus macaque CD28 Protein, His Tag, active dimer, low endotoxin (MALS verified)
HOT CD8-H82E5	Human / Cynomolgus / Rhesus macaque	HEK293	Biotinylated Human / Cynomolgus / Rhesus macaque CD28 Protein, His,Avitag™, active dimer (MALS verified)
HOT CD8-H82F2	Human / Cynomolgus / Rhesus macaque	HEK293	Biotinylated Human / Cynomolgus / Rhesus macaque CD28 Protein, Fc,Avitag™, active dimer (HPLC verified)
CD8-AHFC1	Mouse	HEK293	APC-Labeled Monoclonal Anti-Human CD28 Antibody, Mouse IgG1 (0.03% Proclin)
CD8-BM225	Mouse	HEK293	Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag™, premium grade
CD8-C112GN	Mouse	HEK293	Monoclonal Anti-Human CD28 Antibody, Research Grade
CD8-M120b	Mouse	HEK293	Monoclonal Anti-Human CD28 Antibody, premium grade
CD8-M5258	Mouse	HEK293	Mouse CD28 Protein, Fc Tag (MALS & BLI verified)
CD8-M52H6	Mouse	HEK293	Mouse CD28 Protein, His Tag, active dimer (MALS verified)

총 수량16

CD28분자 배경

T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

CD28분자 별명

CD28,Tp44

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Nezastomig	REGN-5678	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Carcinoma, Renal Cell; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant	상세
Abatacept (Orban Biotech)		Phase 2 Clinical	Orban Biotech, The National Institute Of Diabetes And Digestive And Kidney Diseases	Diabetes Mellitus, Type 1	상세
Lulizumab pegol	Lulizumab; BMS-931699	Phase 2 Clinical	Bristol-Myers Squibb Company	Lupus Vulgaris; Rejection of renal transplantation; Sjogren-Larsson Syndrome	상세
Acazicolcept	ALPN-101	Phase 2 Clinical	Alpine Immune Sciences Inc	Autoimmune Diseases; Graft vs Host Disease; Inflammation; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders	상세
MDX-2003	MDX-2003	Phase 2 Clinical	ModeX Therapeutics Inc	Autoimmune Diseases; Leukemia, B-Cell; Lymphoma; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Primary mediastinal B cell lymphoma; Waldenstrom Macroglobulinemia	상세
Pegrizeprument	FR-104; JNJ-3133; VEL-101	Phase 2 Clinical	Effimune	Arthritis, Rheumatoid; Postoperative Complications; Rejection of renal transplantation	상세
TC-510	TC-510	Phase 2 Clinical	Tcr2 Therapeutics Inc	Carcinoma, Non-Small-Cell Lung; Cholangiocarcinoma; Colorectal Neoplasms; Mesothelioma; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours; Triple Negative Breast Neoplasms	상세
REGN-17372	REGN17372; REGN-17372	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Multiple Myeloma	상세
ZGGS-34	ZGGS34; ZGGS-34	Phase 2 Clinical	Suzhou Zelgen Biopharmaceuticals Co Ltd	Solid tumours	상세
REGN-7945	REGN7945; REGN-7945	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Multiple Myeloma	상세
MDX-2001	MDX2001; MDX-2001	Phase 2 Clinical	ModeX Therapeutics Inc	Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Kidney Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Thyroid Neoplasms; Uterine Cervical Neoplasms	상세
Marlotamig	REGN-7075	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Solid tumours	상세
REGN-5668	REGN-5668	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Endometrial Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms	상세
ATLCAR.k.CD28 cells (UNC Lineberger Comprehensive Cancer Center)		Phase 1 Clinical	Unc Lineberger Comprehensive Cancer Center	Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin	상세
SAR-442257	SAR-442257	Phase 1 Clinical	Sanofi	Neoplasms	상세
Autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells (City of Hope Medical Center)		Phase 1 Clinical	City Of Hope National Medical Center	Lymphoma, Non-Hodgkin	상세
B7-H3.CD28Z.CART therapy (Band Of Parents)		Phase 1 Clinical	The Band Of Parents	Neuroblastoma; Solid tumours	상세
HLX-3901	HLX-3901	Phase 1 Clinical	Shanghai Henlius Biotech Inc	Carcinoma, Neuroendocrine; Neoplasm Metastasis; Small Cell Lung Carcinoma; Solid tumours	상세
SSS-59	SSS59; SSS-59	Phase 1 Clinical	Shenyang Sunshine Pharmaceutical Co Ltd	Neoplasms	상세
RNDO-564	RNDO-564	Phase 1 Clinical	Rondo Therapeutics	Carcinoma; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms	상세
SAR-446422	SAR446422; SAR-446422	Phase 1 Clinical	Sanofi	Autoimmune Diseases	상세
JNJ-1493	JNJ-1493	Phase 1 Clinical	Xencor Inc	Hematologic Neoplasms; Lymphoma, B-Cell	상세
JNJ-9401	JNJ-9401	Phase 1 Clinical	Xencor Inc	Prostatic Neoplasms	상세
SM-2275	SM-2275; SM2275	Phase 1 Clinical	Zhuhai StarMab BioMed Technology Ltd	Solid tumours	상세
JNJ-87189401	JNJ-87189401	Phase 1 Clinical	Janssen Research & Development Llc	Prostatic Neoplasms	상세
REGN5837	REGN5837; REGN-5837	Phase 1 Clinical	Regeneron Pharmaceuticals Inc	Lymphoma, Non-Hodgkin	상세
CC-312	CC-312	Phase 1 Clinical	CytoCares (Shanghai) Inc	Anemia, Hemolytic, Autoimmune; Arthritis, Rheumatoid; Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lupus Erythematosus, Systemic; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Myositis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Scleroderma, Systemic	상세
XmAb-808	XmAb808	Phase 1 Clinical	Xencor Inc	Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Melanoma; Prostatic Neoplasms, Castration-Resistant; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms	상세
SAR-443216	SAR-443216	Phase 1 Clinical	Sanofi	Breast Neoplasms; Lung Neoplasms; Neoplasms; Solid tumours; Stomach Neoplasms	상세
CD19 PD-1/CD28 CAR-T Cell Therapy (Second Affiliated Hospital School Of Zhejiang University School Of Medicine)		Phase 1 Clinical	Second Affiliated Hospital Of Zhejiang University School Of Medicine	Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Primary mediastinal B cell lymphoma	상세
B7-2/GM-CSF cancer gene therapy	CIT	Phase 1 Clinical	Radient	Neoplasms	상세
InHeAb-01	InHeAb-01; bsAB	Clinical	University Hospital Tuebingen	Neoplasms	상세