언어 선택

CD206

CD206 분자 정보

영어 이름	Macrophage mannose receptor 1	시판 약물 수	1
임상 약물 수	2	표적 별명	C-type lectin domain family 13 member D，CLEC13D，Macrophage mannose receptor 1-like protein 1，hMR，Macrophage mannose receptor 1，C-type lectin domain family 13 member D-like，CLEC13DL，MRC1L1，MRC1，Mannose Receptor C-Type 1，Mannose Receptor， C Type 1-Like 1，Human Mannose Receptor，MMR，Mannose Receptor， C Type 1，CD206 Antigen，BA541I19.1，CD206
최고 연구 개발 단계	Approved

영어 이름	Macrophage mannose receptor 1
표적 별명	C-type lectin domain family 13 member D，CLEC13D，Macrophage mannose receptor 1-like protein 1，hMR，Macrophage mannose receptor 1，C-type lectin domain family 13 member D-like，CLEC13DL，MRC1L1，MRC1，Mannose Receptor C-Type 1，Mannose Receptor， C Type 1-Like 1，Human Mannose Receptor，MMR，Mannose Receptor， C Type 1，CD206 Antigen，BA541I19.1，CD206
시판 약물 수	1
임상 약물 수	2
최고 연구 개발 단계	Approved

CD206 제품 목록

속성
Protein (7)
제품 라이브러리
온라인 (7)
종
Human (3)Mouse (2)Cynomolgus (2)
태그
His Tag (4)His Tag & Avi Tag (3)
마커
Unconjugated (3)Biotin-labeled (4)

제품 번호	종	발현 시스템	제품 설명
HOT CD6-H52H9	Human	HEK293	Human CD206 / MMR Protein, His Tag, low endotoxin (MALS verified)
HOT CD6-H82E4	Human	HEK293	Biotinylated Human CD206 / MMR Protein, His,Avitag™
HOT CD6-H82H6	Human	HEK293	Biotinylated Human CD206 / MMR Protein, His Tag, ultra sensitivity (primary amine labeling) (MALS verified)
HOT CD6-M52H7	Mouse	HEK293	Mouse CD206 / MMR Protein, His Tag (HPLC verified)
CD6-M82E8	Mouse	HEK293	Biotinylated Mouse CD206 / MMR Protein, His,Avitag™ (HPLC verified)
CD6-C52H7	Cynomolgus	HEK293	Cynomolgus CD206 / MMR Protein, His Tag (MALS verified)
CD6-C82E4	Cynomolgus	HEK293	Biotinylated Cynomolgus CD206 / MMR Protein, His,Avitag™ (MALS verified)

총 수량7

CD206분자 배경

Mrc1 is a conserved checkpoint mediator protein that transduces the replication stress signal to the downstream effector kinase. Mrc1 and its vertebrate homologue Claspin serve as a mediator for replication stress checkpoint signaling, receiving the signal from Mec1/Rad3/ATR sensor kinase and transmitting it to the effector Rad53/Cds1/Chk1 kinase. The loss of mrc1 checkpoint activity results in the aberrant activation of late/dormant origins in the presence of hydroxyurea. Tumor-associated macrophages (TAMs) expressing the multi-ligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immunosuppression, angiogenesis, metastasis, and relapse.

CD206분자 별명

MMR,CD206,hMR,MRC1,CLEC13D,CLEC13DL,MRC1L1

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
68Ga-tilmanocept		Phase 3 Clinical	Navidea Biopharmaceuticals Inc	Atherosclerosis; Carcinoma, Endometrioid; Endometrial Neoplasms; Tuberculosis	상세
68GaNOTA-Anti-MMR-VHH2		Phase 2 Clinical	Universitair Ziekenhuis Brussel	Atherosclerosis; Carcinoma, Non-Small-Cell Lung; Carotid Stenosis; Hodgkin Disease; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoidosis	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Technetium Tc 99m tilmanocept	NEO3-09	Approved	University Of California	Lymphoseek Kit, Lymphoseek, Lymphoaim	United States	Solid tumours; Diagnostic agents; Breast Neoplasms; Melanoma; Carcinoma, Squamous Cell; Head and Neck Neoplasms	Cardinal Health 414 Llc	2013-03-13	Anus Neoplasms; Arthritis, Rheumatoid; Breast Neoplasms; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Colonic Neoplasms; Colorectal Neoplasms; Diagnostic agents; Endometrial Neoplasms; Head and Neck Neoplasms; HIV Infections; Liver Neoplasms; Melanoma; Metabolic Dysfunction-Associated Steatotic Liver Disease; Rectal Neoplasms; Sarcoidosis; Sarcoma, Kaposi; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Uterine Cervical Neoplasms	상세