CCL24

CCL24 분자 정보

영어 이름Chemokine (C-C Motif) Ligand 24시판 약물 수0
임상 약물 수1표적 별명Small Inducible Cytokine Subfamily A (Cys-Cys), Member 24,Chemokine (C-C Motif) Ligand 24,Small-Inducible Cytokine A24,MPIF-2,Ckb-6,Chemokine CCL24,MPIF2,SCYA24,Eotaxin-2,CK-beta-6,Myeloid progenitor inhibitory factor 2,C-C motif chemokine 24,CCL24,C-C Motif Chemokine Ligand 24,Eosinophil Chemotactic Protein 2
최고 연구 개발 단계Phase 2 Clinical
영어 이름Chemokine (C-C Motif) Ligand 24
표적 별명Small Inducible Cytokine Subfamily A (Cys-Cys), Member 24,Chemokine (C-C Motif) Ligand 24,Small-Inducible Cytokine A24,MPIF-2,Ckb-6,Chemokine CCL24,MPIF2,SCYA24,Eotaxin-2,CK-beta-6,Myeloid progenitor inhibitory factor 2,C-C motif chemokine 24,CCL24,C-C Motif Chemokine Ligand 24,Eosinophil Chemotactic Protein 2
시판 약물 수0
임상 약물 수1
최고 연구 개발 단계Phase 2 Clinical

CCL24 제품 목록

  • 속성

    Protein (1)

  • 제품 라이브러리

    온라인 (1)

  • Human (1)

  • 태그

    His Tag (1)

  • 마커

    Unconjugated (1)

제품 번호발현 시스템제품 설명단백질 구조순도특성
CC4-H52H1
Human
HEK293
Human CCL24/Eotaxin-2 Protein, His Tag (HPLC verified)
총 수량1
  • 1

CCL24분자 배경

C-C motif chemokine ligand 24 (CCL24), also known as eotaxin2, belongs to CC chemokines like MCP-1, and it mainly chemoattracts eosinophils. CCL24 can promote the separation of eosinophils from endothelial cells and then combine with its sole ligand to promote eosinophils to enter the tissue. CCL24 was not originally found in eosinophils but was first isolated from monocytes. Latest, it was found that the expression of CCL24 in the bronchial epithelial cells of asthma patients increased. CCL24 promotes immune cell trafficking and activation as well as profibrotic activities through the CCR3 receptor (C-C chemokine receptor type 3). Both CCL24 and CCR3 is involved in lung and skin inflammation and fibrosis.

CCL24분자 별명

C-C motif chemokine 24,CK-beta-6,Eosinophil chemotactic protein 2,Myeloid progenitor inhibitory factor 2,Small-inducible cytokine A24,Eotaxin-2,MPIF-2,SCYA24,MPIF2

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
NebokitugCM-101Phase 2 ClinicalChemomab Therapeutics LtdCholangitis, Sclerosing; Metabolic Dysfunction-Associated Steatotic Liver Disease; Scleroderma, Systemic
상세
  • 분자 정보
  • 제품 목록
  • 임상 약물 정보
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