Mouse TPBG / 5T4 Protein, His Tag (MALS verified)

제품 번호/규격
가격
Availability
수량
TPG-M52H3-100ug
$360.00
In Stock - Delivery in 1-2 business days
TPG-M52H3-1mg
$2,615.00
In Stock - Delivery in 1-2 business days
TPG-M52H3
제품 금액 :
$ 0
신제품 제안 Request Quote
Contact Us
Contact Us
제품 금액:
$ 0
  • 제품 세부정보
  • 데이터 표시
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

TPBG, 5T4, M6P1, 5T4AG, WAIF1, 5T4 oncofetal antigen, Trophoblast glycoprotein, 5T4 oncofetal trophoblast glycoprotein

Source

Mouse TPBG, His Tag (TPG-M52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 32 - Ser 361 (Accession # Q9Z0L0-1).

Predicted N-terminus: Ser 32

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 37.7 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

배경 소개

Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.