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MASP3, MASP1, CRARF1, RaRF
Human MASP3, His Tag (MA3-H5243) is expressed from human 293 cells (HEK293). It contains AA Gly 298 - Val 721 (Accession # P48740-2).
Predicted N-terminus: His
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 48.7 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Less than 1.0 EU per μg by the LAL method.
>95% as determined by SDS-PAGE.
Delivered as bulk protein in a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, pH8.0 with trehalose as protectant.
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This product is supplied as sterile liquid solution and shipped frozen with dry ice.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
MASP3 is a member of the MASP family. The MASP family proteins were first discovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associated serine proteases, but later, they were found to interact with ficolins, and later still, collectin-10 and collectin-11. As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includes non-enzymatic factors (MAp19, MAp44). In this review, the association-specific factors of the lectin pathway with haematologic malignancies and related infections are discussed.