CCL4

CCL4 분자 정보

영어 이름C-C motif chemokine 4시판 약물 수0
임상 약물 수0표적 별명LAG1,Secreted Protein G-26,Chemokine (C-C Motif) Ligand 4,C-C Motif Chemokine Ligand 4,AT744.1,ACT2,SCYA4,G-26,G-26 T-lymphocyte-secreted protein,HC21,Lymphocyte activation gene 1 protein,LAG-1,MIP-1-beta(1-69),Macrophage inflammatory protein 1-beta,MIP-1-beta,PAT 744,Protein H400,T-cell activation protein 2,ACT-2,SCYA2,MIP1B1,MIP1B,SIS-gamma,Small-inducible cytokine A4
최고 연구 개발 단계Preclinical
영어 이름C-C motif chemokine 4
표적 별명LAG1,Secreted Protein G-26,Chemokine (C-C Motif) Ligand 4,C-C Motif Chemokine Ligand 4,AT744.1,ACT2,SCYA4,G-26,G-26 T-lymphocyte-secreted protein,HC21,Lymphocyte activation gene 1 protein,LAG-1,MIP-1-beta(1-69),Macrophage inflammatory protein 1-beta,MIP-1-beta,PAT 744,Protein H400,T-cell activation protein 2,ACT-2,SCYA2,MIP1B1,MIP1B,SIS-gamma,Small-inducible cytokine A4
시판 약물 수0
임상 약물 수0
최고 연구 개발 단계Preclinical

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CCL4분자 배경

CCL4, also know as MIP-1-beta, is monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B

CCL4분자 별명

C-C motif chemokine 4,G-26 T-lymphocyte-secreted protein,HC21,Lymphocyte activation gene 1 protein,LAG-1,MIP-1-beta(1-69),Macrophage inflammatory protein 1-beta,MIP-1-beta,PAT 744,Protein H400,SIS-gamma,Small-inducible cytokine A4,T-cell activation protei
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