Mouse TSLP Protein, His Tag (MALS verified)

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제품 번호/규격
가격
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TSP-M52H8-100ug
$380.00
TSP-M52H8-1mg
$2615.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    TSLP

  • Source

    Mouse TSLP, His Tag (TSP-M52H8) is expressed from human 293 cells (HEK293). It contains AA Tyr 20 - Glu 140 (Accession # Q9JIE6-1).

    Predicted N-terminus: Tyr 20

    Request for sequence
  • Molecular Characterization

    TSLP Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 15.9 kDa. The protein migrates as 23-27 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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데이터 표시

  • SDS-PAGE

    TSLP SDS-PAGE

    Mouse TSLP, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    TSLP SEC-MALS

    The purity of Mouse TSLP, His Tag (Cat. No. TSP-M52H8) is more than 90% and the molecular weight of this protein is around 18-28 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     TSLP ELISA

    Immobilized Mouse TSLP, His Tag (Cat. No. TSP-M52H8) at 1 μg/mL (100 μL/well) can bind Recombinant Mouse TSLPR Fc Chimera Protein with a linear range of 0.06-2 ng/mL (QC tested).

    Protocol

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댓글 남기기

  • S***n2023-06-10
    좋아요
    We got the TSLP recombinant protein from your company. The plan was to stimulate cell in vitro to see if it can induce a TH2 response. Your company offers the most cost effective option for the TSLP protein and with good customer service and express shipping. So far we do see some level of responses in the cells, we will perform more testing to validate the effects. The quality of the protein seems quite good and worth trying.

배경 소개

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Thymic stromal lymphopoietin

  • 카테고리:

  • 상장 의약품 수:

    1 상세

  • 임상 의약품 수:

    29 상세

  • 최고 개발 단계:

    Approved

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