Biotinylated Human TRBC1 Protein, His,Avitag™

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Cat. No. / Size
Price
Qty
TR1-H82E6-25ug
$360.00
TR1-H82E6-200ug
$1420.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    T cell receptor beta constant 1, TRBC1

  • Source

    Biotinylated Human TRBC1, His,Avitag (TR1-H82E6) is expressed from human 293 cells (HEK293). It contains AA Asp 1 - Ala 144 (Accession # P01850-1).

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  • Molecular Characterization

    TRBC1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 19.9 kDa. The protein migrates as 23 kDa and 26 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Endotoxin

    Less than 0.2 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

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  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    TRBC1 SDS-PAGE

    Biotinylated Human TRBC1, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

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Background

The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain. Each polypeptide chain consists of a variable and a constant region. TRBC1 is the constant region of T-cell receptor (TCR) beta chain. TRBC1 is presented on the surface of T cell and recognized peptide-major histocompatibility (MH) (pMH) that are displayed by antigen presenting cells (APC). TRBC1 is participate in an adaptive immune response and has been well-studied in T cell therapy.

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Drug Development Progress
  • English Name:

    TRBC1

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  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    5 Details

  • Highest Development Stage:

    Phase 2 Clinical

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