Product Details
Synonyms
CD267, TACI, TNFRSF13B
Source
Biotinylated Human TACI Protein, Fc,Avitag (TAL-H82F3) is expressed from human 293 cells (HEK293). It contains AA Ser 2 - Thr 166 (Accession # O14836-1(R119A,R122A)).
Predicted N-terminus: Ser 2
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
The protein has a calculated MW of 46.5 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Labeling
Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
Protein Ratio
Passed as determined by the HABA assay / binding ELISA.
Purity
>90% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE

Biotinylated Human TACI Protein, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS

The purity of Biotinylated Human TACI Protein, Fc,Avitag (Cat. No. TAL-H82F3) is more than 95% and the molecular weight of this protein is around 45-65 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Human BAFF Protein, Fc Tag (Cat. No. BAF-H5261) at 5 μg/mL (100 μL/well) can bind Biotinylated Human TACI Protein, Fc,Avitag (Cat. No. TAL-H82F3) with a linear range of 0.2-5 ng/mL (QC tested).
Protocol
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Background
The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.
Recent Advances
- English Name:
Tumor necrosis factor receptor superfamily member 13B
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
0 Details
- Highest Development Stage:
Preclinical
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