Human Syndecan-1 Protein, His Tag

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SY1-H5225-100ug
$360.00
In Stock - Delivery in 2-3 business days
SY1-H5225-1mg (500ug X 2)
$2615.00
In Stock - Delivery in 2-3 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    SDC1, Syndecan-1, CD138, SYND1, SDC

  • Source

    Human Syndecan-1, His Tag (SY1-H5225) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 254 (Accession # P18827-1).

    Predicted N-terminus: Gln 23

    Request for sequence
  • Molecular Characterization

    Syndecan-1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 25.8 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.1 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    Syndecan-1 SDS-PAGE

    Human Syndecan-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • Bioactivity-ELISA

     Syndecan-1 ELISA

    Immobilized Human Syndecan-1, His Tag (Cat. No. SY1-H5225) at 1 μg/mL (100 μL/well) can bind Anti-Syndecan-1 antibody, Mouse IgG1 with a linear range of 0.1-3 ng/mL (QC tested).

    Protocol
  •  Syndecan-1 ELISA

    Immobilized Anti-Syndecan-1 antibody, Mouse IgG1 at 1 μg/mL (100 μL/well) can bind Human Syndecan-1, His Tag (Cat. No. SY1-H5225) with a linear range of 2-125 ng/mL (Routinely tested).

    Protocol
  • Bioactivity-FACS

     Syndecan-1 FACS

    2e5 of anti-Syndecan-1 CAR-293 cells were stained with 100 μL of 3 μg/mL of Human Syndecan-1, His Tag (Cat. No. SY1-H5225) and negative control protein respectively, washed and then followed by PE anti-His Tag antibody and analyzed with FACS (Routinely tested).

    Protocol

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배경 소개

Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Syndecan-1

  • 카테고리:

  • 상장 의약품 수:

    0 상세

  • 임상 의약품 수:

    2 상세

  • 최고 개발 단계:

    Phase 1 Clinical

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