SARS-CoV Spike Trimer Protein (S353F, R667A, KV968-969PP), His Tag

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제품 번호/규격
가격
수량
SPN-S5221-100ug
$336.00
SPN-S5221-1mg
$2184.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    Spike, S protein, Spike glycoprotein, S glycoprotein

  • Source

    SARS-CoV Spike Trimer Protein, His Tag (SPN-S5221) is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # P59594 (S353F, R667A, KV968-969PP)).

    Predicted N-terminus: Ser 14

    Request for sequence
  • Molecular Characterization

    Spike protein Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 136.4 kDa. The protein migrates as 150-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 0.1 M Sodium citrate, pH5.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    Spike protein SDS-PAGE

    SARS-CoV Spike Trimer Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • Bioactivity-ELISA

     Spike protein ELISA

    Immobilized Human ACE2, Fc Tag (Cat. No. AC2-H5257) at 5 μg/mL (100 μL/well) can bind SARS-CoV Spike Trimer Protein, His Tag (Cat. No. SPN-S5221) with a linear range of 0.008-1 μg/mL (QC tested).

    Protocol

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배경 소개

The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Coronavirus spike glycoprotein

  • 카테고리:

  • 상장 의약품 수:

    15 상세

  • 임상 의약품 수:

    88 상세

  • 최고 개발 단계:

    Approved

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  • 고객님도 확인한 상품
  • 데이터 표시
  • 사용자 리뷰
  • 배경
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