Human SMN1 Protein, His Tag

사용자 리뷰
제품 번호/규격
가격
수량
SM1-H5145-100ug
$310.00
SM1-H5145-1mg (500ug X 2)
$2040.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    Survival Motor Neuron 1, SMN1

  • Source

    Human SMN1, His Tag (SM1-H5145) is expressed from E. coli cells. It contains AA Ala 2 - Asn 294 (Accession # Q16637-1).

    Predicted N-terminus: Met

    Request for sequence
  • Molecular Characterization

    SMN1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 33.7 kDa. The protein migrates as 36-40 kDa and 69 kDa under reducing (R) condition (SDS-PAGE).

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 0.5 M Arginine, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    SMN1 SDS-PAGE

    Human SMN1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • Bioactivity-ELISA

     SMN1 ELISA

    Immobilized Human SMN1, His Tag (Cat. No. SM1-H5145) at 1 μg/mL (100 μL/well) can bind Anti-SMN1 antibody with a linear range of 0.2-8 ng/mL (QC tested).

    Protocol

사용자 리뷰
댓글 남기기

배경 소개

SMN1 is produced chiefly by the SMN1 gene, located on the telomeric portion of chromosome 5q. SMN1 protein is one of a group of proteins called the SMN complex, which is important for the maintenance of specialized nerve cells called motor neurons. In cells, the SMN complex plays an important role in processing mRNA. The SMN complex helps to assemble the cellular machinery needed to process pre-mRNA. The SMN complex is also important for the development of specialized outgrowths from nerve cells called dendrites and axons. Deletion or mutation of the SMN1 gene results in a reduced level of full-length SMN protein and manifests as a range of neuromuscular phenotypes in humans as the disease spinal muscular atrophy (SMA).

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Survival motor neuron protein

  • 카테고리:

  • 상장 의약품 수:

    4 상세

  • 임상 의약품 수:

    9 상세

  • 최고 개발 단계:

    Approved

연락하기
신약 후보물질 라이선싱
더 많이 알아보기
  • 기본 제품 정보
  • 제품 세부정보
  • 고객님도 확인한 상품
  • 데이터 표시
  • 사용자 리뷰
  • 배경
문의하기

전화
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521

주소 서울특별시 송파구 법원로11길 11, 제3층 제비-314,315호