Human ROCK1 Protein, GST Tag (active enzyme)

제품 번호/규격
가격
Availability
수량
RO1-H5533-10ug
$330.00
RO1-H5533-50ug
$960.00
In Stock - Delivery in 2-3 weeks
RO1-H5533
제품 금액 :
$ 0
신제품 제안 Request Quote
Contact Us
Contact Us
제품 금액:
$ 0
  • 제품 세부정보
  • 데이터 표시
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

ROCK1

Source

Human ROCK1 Protein, GST Tag (RO1-H5533) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Leu 535 (Accession # Q13464).

Predicted N-terminus: Met

Molecular Characterization

This protein carries a GST tag at the N-terminus.

The protein has a calculated MW of 88.2 kDa. The protein migrates as 90-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>50% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, PH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.

배경 소개

ROCK1 (Rho-associated coiled-coil containing protein kinase 1) is a critical serine/threonine kinase that functions as a key downstream effector of the small GTPase RhoA. It plays a fundamental role in regulating cytoskeleton organization, actomyosin contractility, and cell motility. ROCK1 is vital for diverse biological processes, including cell adhesion, cytokinesis, and apoptosis, making it a significant target in cancer and cardiovascular research.

ACRO Scientific Leadership Award

Supporting the scientists driving cell & gene therapy forward

Apply Now