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Human ROCK1 Protein, GST Tag (active enzyme)

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RO1-H5533-10ug
$330.00
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RO1-H5533-50ug
$960.00
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RO1-H5533
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

ROCK1

Source

Human ROCK1 Protein, GST Tag (RO1-H5533) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Leu 535 (Accession # Q13464).

Predicted N-terminus: Met

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a GST tag at the N-terminus.

The protein has a calculated MW of 88.2 kDa. The protein migrates as 90-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>50% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, PH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.
ACRO Quality Management System

Background

ROCK1 (Rho-associated coiled-coil containing protein kinase 1) is a critical serine/threonine kinase that functions as a key downstream effector of the small GTPase RhoA. It plays a fundamental role in regulating cytoskeleton organization, actomyosin contractility, and cell motility. ROCK1 is vital for diverse biological processes, including cell adhesion, cytokinesis, and apoptosis, making it a significant target in cancer and cardiovascular research.