Rabies virus (strain CVS-11) Nucleoprotein, His Tag

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NUN-R55H4-100ug
$465.00
NUN-R55H4-1mg
$2885.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    Nucleoprotein

  • Source

    Rabies virus (strain CVS-11) Nucleoprotein, His Tag (NUN-R55H4) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Ser 450 (Accession # Q8JXF6).

    Predicted N-terminus: Met

    Request for sequence
  • Molecular Characterization

    Nucleoprotein Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 52.7 kDa. The protein migrates as 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50 mM Tris, 500 mM NaCl, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping and Storage

    This product is supplied and shipped on dry ice.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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데이터 표시

  • SDS-PAGE

    Nucleoprotein SDS-PAGE

    Rabies virus (strain CVS-11) Nucleoprotein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • Bioactivity-ELISA

     Nucleoprotein ELISA

    Immobilized Rabies virus (strain CVS-11) Nucleoprotein, His Tag (Cat. No. NUN-R55H4) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Rabies virus Nucleoprotein Antibody, Mouse IgG1 (10B6) (Cat. No. NUN-MY311) with a linear range of 0.2-8 ng/mL (QC tested).

    Protocol

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배경 소개

Rabies virus (RABV), scientific name Rabies lyssavirus, is a deadly neurotropic virus that causes rabies in humans and animals. Rabies virus has an extremely wide host range and its transmission most often occur through the saliva of animals. Without intervention prior to disease progression, rabies has the highest case fatality of any infectious disease. RABV contains a single-stranded negative-sense RNA genome that encodes five structural proteins: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G), and RNA-dependent RNA polymerase (L). RABV N protein is 450 amino acids long and serves the critical function of tightly packaging the RNA genome into an RNase-resistant core. Encapsidation of the genomic RNA by newly synthesized N is believed to switch viral RNA from transcription to replication. Furthermore, N is a major antigen for RABV to stimulate Th cells and antibody production.

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주소 서울특별시 송파구 법원로11길 11, 제3층 제비-314,315호