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SARS-CoV-2 (COVID-19) NSP7&NSP8 Protein, His Tag

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NS8-C5125-100ug
$410.00
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NS8-C5125-1mg (200ug X 5)
$2,945.00
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NS8-C5125
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  • 제품 세부정보
  • 데이터 표시
  • Reviews & Citations
  • Important Statement
  • Resources

  • Synonyms

    NSP7 & NSP8, nsp7 & nsp8

  • Source

    SARS-CoV-2 NSP7&NSP8, His Tag (NS8-C5125) is expressed from E. coli cells. It contains AA Ser 1 - Gln 83 (NSP7) & Ala 1 - Gln 198 (NSP8) (Accession # YP_009725303.1 (NSP7) & YP_009725304.1 (NSP8)).

    Predicted N-terminus: Met

    Request for sequence

  • Molecular Characterization

    This protein carries a polyhistidine tag.

    The protein has a calculated MW of 32.1 kDa. The protein migrates as 28-32 kDa under reducing (R) condition (SDS-PAGE).

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

배경 소개

During the formation of the coronaviral replication/transcription complex, essential steps include processing of the conserved polyprotein nsp7-10 region by the main protease Mpro and subsequent complex formation of the released nsp's. Upon infecting host cells, coronaviruses assemble a multi-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replication and transcription of the viral genome. non-structural proteins 7 (NSP7) forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.