Mouse MMP-2 Protein, Fc Tag (Pro-form, MALS verified)

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MM2-M5253-50ug
$275.00
In Stock - Delivery in 2-3 business days
MM2-M5253-1mg
$1980.00
In Stock - Delivery in 2-3 weeks
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1

  • Source

    Mouse MMP-2 Protein, Fc Tag (MM2-M5253) is expressed from human 293 cells (HEK293). It contains AA Ala 30 - Cys 662 (Accession # P33434-1). It needs to be activated by agents such as APMA in vitro to have hydrolytic activity.

    Predicted N-terminus: Ala 30

    Request for sequence

  • Molecular Characterization

    MMP-2 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 97.5 kDa. The protein migrates as 95-110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping and Storage

    This product is supplied and shipped on dry ice.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    MMP-2 SDS-PAGE

    Mouse MMP-2 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    MMP-2 SEC-MALS

    The purity of Mouse MMP-2 Protein, Fc Tag (Cat. No. MM2-M5253) is more than 90% and the molecular weight of this protein is around 185-235 kDa verified by SEC-MALS.

    Report
  • Bioactivity

    Measured by its ability to cleave the fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2. The specific activity is >800 pmol/min/µg (QC tested).

    Protocol

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배경 소개

MMP-2 (Matrix Metalloproteinase-2), also known as Gelatinase A, is a key enzyme belonging to the matrix metalloproteinase (MMP) family. MMPs are zinc-dependent endopeptidases primarily responsible for the degradation of components of the extracellular matrix (ECM), such as collagen, gelatin, and fibronectin.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Matrix metalloproteinase-2

  • 카테고리:

  • 상장 의약품 수:

    0 상세

  • 임상 의약품 수:

    1 상세

  • 최고 개발 단계:

    Phase 1 Clinical

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