Human Matriptase / ST14 Catalytic Domain Protein, His Tag (active enzyme)

사용자 리뷰
제품 번호/규격
가격
Availability
수량
MAE-H5143-100ug
$415.00
In Stock - Delivery in 2-3 business days
MAE-H5143-1mg
$2855.00
In Stock - Delivery in 2-3 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    Matriptase

  • Source

    Human Matriptase / ST14 Catalytic Domain Protein, His Tag (MAE-H5143) is expressed from E. coli cells. It contains AA Gly 596 - Val 855 (Accession # NP_068813).

    Predicted N-terminus: Met

    Request for sequence
  • Molecular Characterization

    Matriptase Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 30.6 kDa. The protein migrates as 27-28 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, Trehalose, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping and Storage

    This product is supplied and shipped on dry ice.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    Matriptase SDS-PAGE

    Human Matriptase / ST14 Catalytic Domain Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • Bioactivity

    Measured by its ability to cleave the fluorogenic peptide substrate Boc-QAR-AMC . The specific activity is >15,000 pmol/min/μg (QC tested).

    Protocol

사용자 리뷰
댓글 남기기

배경 소개

Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing; Cleaves various synthetic substrates with Arg or Lys at the P1 position and prefers small side-chain amino acids, such as Ala and Gly, at the P2 position.

프론티어 진행

 
연락하기
신약 후보물질 라이선싱
더 많이 알아보기
  • 기본 제품 정보
  • 제품 세부정보
  • 고객님도 확인한 상품
  • 데이터 표시
  • 사용자 리뷰
  • 배경
문의하기

전화
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521

주소 서울특별시 송파구 법원로11길 11, 제3층 제비-314,315호