Product Details
Synonyms
A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R, IGFBP3R1, KPA, LRP, LRP1A, TGFBR5
Source
Biotinylated Human cluster Ⅳ Protein, His,Avitag (LR1-H82E4) is expressed from human 293 cells (HEK293). It contains AA Ser 3332 - Asp 3779 (Accession # Q07954-1).
Predicted N-terminus: Ser 3332
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
The protein has a calculated MW of 53.7 kDa. The protein migrates as 60 kDa and 65-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Labeling
Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
Protein Ratio
Passed as determined by the HABA assay / binding ELISA.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE

Biotinylated Human cluster Ⅳ Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
Bioactivity-BLI

Loaded Biotinylated Human cluster Ⅳ Protein, His,Avitag (Cat. No. LR1-H82E4) on SA Biosensor, can bind Human PDGF-BB, premium grade (Cat. No. PDB-H4112) with an affinity constant of 48.3 nM as determined in BLI assay (ForteBio Octet R8) (QC tested).
Protocol
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Background
Recent Advances
- English Name:
Low density lipoprotein receptor-related protein-1
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
0 Details
- Highest Development Stage:
Preclinical
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