Biotinylated Human LILRA1 / CD85i / LIR-6 Protein, His,Avitag™

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제품 번호/규격
가격
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LI1-H82E8-25ug
$360.00
LI1-H82E8-200ug
$1565.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    LILRA1, LIR6, CD85i, LIR-6

  • Source

    Biotinylated Human LILRA1, His,Avitag (LI1-H82E8) is expressed from human 293 cells (HEK293). It contains AA Pro 17 - Asn 461 (Accession # O75019-1).

    Predicted N-terminus: Pro 17

    Request for sequence
  • Molecular Characterization

    LILRA1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 52.2 kDa. The protein migrates as 60-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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데이터 표시

  • SDS-PAGE

    LILRA1 SDS-PAGE

    Biotinylated Human LILRA1, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • Bioactivity-BLI

     LILRA1 BLI

    Loaded Biotinylated Human LILRA1, His,Avitag (Cat. No. LI1-H82E8) on SA Biosensor, can bind Human ANGPTL7, His Tag with an affinity constant of 0.204 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

    Protocol

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배경 소개

Leukocyte immunoglobulin-like receptors (LILRs) are inhibitory, stimulatory or soluble receptors encoded within the leukocyte receptor complex. Some LILRs are extensively polymorphic, and exhibit evidence for balancing selection and association with disease susceptibility. LILRA1 (LIR-6) can recognize MHC (major histocompatibility complex) class I or class I-like molecules, and high levels of sequence similarity among LILRA1, LILRA2 (ILT1), LILRA3 (ILT6) and LILRB1/B2.

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