Cynomolgus IFN-alpha/beta R1 Protein, His Tag (MALS verified)

사용자 리뷰
제품 번호/규격
가격
수량
IF1-C52H3-100ug
$380.00
IF1-C52H3-1mg
$2615.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    IFNAR1, IFNAR, CRF2-1, IFN-R-1, IFNAR-1

  • Source

    Cynomolgus IFN-alpha/beta R1 Protein, His Tag (IF1-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 25 - Lys 437 (Accession # A0A7N9D7J0-1).

    Predicted N-terminus: Ala 25

    Request for sequence
  • Molecular Characterization

    IFN-alpha/beta R1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 49.3 kDa. The protein migrates as 65-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    IFN-alpha/beta R1 SDS-PAGE

    Cynomolgus IFN-alpha/beta R1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    IFN-alpha/beta R1 SEC-MALS

    The purity of Cynomolgus IFN-alpha/beta R1 Protein, His Tag (Cat. No. IF1-C52H3) is more than 85% and the molecular weight of this protein is around 65-85 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     IFN-alpha/beta R1 ELISA

    Immobilized Human IFN-alpha 1, Fc Tag (Cat. No. IFA-H5258) at 5 μg/mL (100 μL/well) can bind Cynomolgus IFN-alpha/beta R1 Protein, His Tag (Cat. No. IF1-C52H3) with a linear range of 5-78 ng/mL (QC tested).

    Protocol
  • Bioactivity-BLI

     IFN-alpha/beta R1 BLI

    Loaded bind Human IFN-alpha 1, Fc Tag (Cat. No. IFA-H5258) on Protein A Biosensor, can bind Cynomolgus IFN-alpha/beta R1 Protein, His Tag (Cat. No. IF1-C52H3) with an affinity constant of 16.5 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

    Protocol

사용자 리뷰
댓글 남기기

배경 소개

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Interferon-alpha/beta receptor alpha chain

  • 카테고리:

  • 상장 의약품 수:

    5 상세

  • 임상 의약품 수:

    0 상세

  • 최고 개발 단계:

    Approved

연락하기
신약 후보물질 라이선싱
더 많이 알아보기
  • 기본 제품 정보
  • 제품 세부정보
  • 고객님도 확인한 상품
  • 데이터 표시
  • 사용자 리뷰
  • 배경
문의하기

전화
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521

주소 서울특별시 송파구 법원로11길 11, 제3층 제비-314,315호