Influenza B virus (Pennsylvania/14/2025) HA (B/Victoria lineage) Protein, His Tag (MALS verified)

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HAB-V52H3-100ug
$350.00
In Stock - Delivery in 2-3 weeks
HAB-V52H3-1mg
$2680.00
In Stock - Delivery in 2-3 weeks
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    HA, Hemagglutinin

  • Source

    Influenza B virus (Pennsylvania/14/2025) HA (B/Victoria lineage) Protein, His Tag (HAB-V52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 16 - Thr 545 (Accession # EPI_ISL_20077099, GISAID).

    Predicted N-terminus: Asp 16

    Request for sequence

  • Molecular Characterization

    Hemagglutinin/HA (Influenza Virus) Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 62.8 kDa . The protein migrates as 80-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

    The protein is designed as a trimer.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Supplied as 0.2 μm filtered solution in 0.1 M Sodium citrate, 0.5 M Arginine, Glycerol, pH5.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping and Storage

    This product is supplied and shipped on dry ice.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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데이터 표시

  • SDS-PAGE

    Hemagglutinin/HA (Influenza Virus) SDS-PAGE

    Influenza B virus (Pennsylvania/14/2025) HA (B/Victoria lineage) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Hemagglutinin/HA (Influenza Virus) SEC-MALS

    The purity of Influenza B virus (Pennsylvania/14/2025) HA (B/Victoria lineage) Protein, His Tag (Cat. No. HAB-V52H3) is more than 90% and the molecular weight of this protein is around 210-250 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Hemagglutinin/HA (Influenza Virus) ELISA

    Immobilized Influenza B virus (Pennsylvania/14/2025) HA (B/Victoria lineage) Protein, His Tag (Cat. No. HAB-V52H3) at 1 μg/mL (100 μL/well) can bind various dilution ratio of Influenza B Hemagglutinin / HA Antibody, Rabbit Mab (QC tested).

    Protocol
  • Bioactivity-SPR

     Hemagglutinin/HA (Influenza Virus) SPR

    Influenza B Hemagglutinin / HA Antibody, Rabbit Mab immobilized on CM5 Chip can bind Influenza B virus (Pennsylvania/14/2025) HA (B/Victoria lineage) Protein, His Tag (Cat. No. HAB-V52H3) with an affinity constant of 0.574 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

    Protocol

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배경 소개

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

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