Biotinylated Human Galectin-9 / LGALS9 Protein, His,Avitag™

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제품 번호/규격
가격
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LG9-H82H3-25ug
$360.00
LG9-H82H3-200ug
$1420.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    Galectin-9, LGALS9, Ecalectin

  • Source

    Biotinylated Human Galectin-9, His,Avitag (LG9-H82H3) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2).

    Predicted N-terminus: His

    Request for sequence
  • Molecular Characterization

    Galectin-9 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 39.3 kDa. The protein migrates as 52-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 20 mM MOPS, 50 mM Nacl, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    Galectin-9 SDS-PAGE

    Biotinylated Human Galectin-9, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • Bioactivity-ELISA

     Galectin-9 ELISA

    Immobilized Biotinylated Human Galectin-9, His,Avitag (Cat. No. LG9-H82H3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Recombinant Antibody Service-Anti-Gal9 Antibody,Human IgG4 L445P-Kappa with a linear range of 0.06-8 ng/mL (Routinely tested).

    Protocol

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배경 소개

Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3Glcc or Galβ1-4Glcc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Galactoside-binding lectin Galectin 9

  • 카테고리:

  • 상장 의약품 수:

    0 상세

  • 임상 의약품 수:

    2 상세

  • 최고 개발 단계:

    Phase 2 Clinical

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