Human Ephrin-B2 / EFNB2 Protein, Fc tag (MALS verified)

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EPN-H5259-50ug
$65.00
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EPN-H5259-500ug
$555.00
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EPN-H5259
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Synonyms

EFNB2

Source

Human Ephrin-B2 Protein, Fc tag (EPN-H5259) is expressed from human 293 cells (HEK293). It contains AA Ser 25 - Ala 168 (Accession # P52799-1).

Predicted N-terminus: Ser 25

Molecular Characterization

This protein carries a human IgG1 Fc tag at the C-terminus.

The protein has a calculated MW of 42.8 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

배경 소개

Ephrin-B2 (EFNB2) is also known as EPH-related receptor tyrosine kinase ligand 5 (LERK-5) or HTK ligand (HTK-L), which belongs to the ephrin family. The ephrin-B (ENFB) class are transmembrane proteins implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. EFNB2 has been shown to interact with EPHA3 and EPHB1 in optic chiasm development. EFNB2 has also been shown to serve as a receptor for Hendra Virus and Nipah Virus, mediating entry into the cell during infection.