Mouse CA125 / MUC16 Protein, His Tag (MALS verified)

제품 번호/규격
가격
수량
CA5-M52H6-100ug
$360.00
CA5-M52H6-1mg (500ug X 2)
$2615.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    CA125, CA-125, CA125MUC-16, FLJ14303, MUC16, mucin 16, mucin-16

  • Source

    Mouse CA125 Protein, His Tag (CA5-M52H6) is expressed from human 293 cells (HEK293). It contains AA Asn 7750 - Pro 8422 (Accession # A0A140LJ72-1).

    Predicted N-terminus: Asn 7750

    Request for sequence
  • Molecular Characterization

    CA125 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 76.7 kDa.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SEC-MALS

    CA125 SEC-MALS

    The purity of Mouse CA125 Protein, His Tag (Cat. No. CA5-M52H6) is more than 90% and the molecular weight of this protein is around 120-140 kDa verified by SEC-MALS.

    Report
  • Bioactivity-SPR

     CA125 SPR

    Biotinylated Mouse Mesothelin, His,Avitag (Cat. No. MSN-M82E7) immobilized on CM5 Chip can bind Mouse CA125 Protein, His Tag (Cat. No. CA5-M52H6) with an affinity constant of 16.4 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

    Protocol

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배경 소개

The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Mucin-16

  • 카테고리:

  • 상장 의약품 수:

    0 상세

  • 임상 의약품 수:

    7 상세

  • 최고 개발 단계:

    Phase 3 Clinical

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  • 배경
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