Mouse B7-H5 / Gi24 / VISTA Protein, His Tag

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B75-M52H7-100ug
$360.00
In Stock - Delivery in 2-3 business days
B75-M52H7-1mg
$2245.00
In Stock - Delivery in 2 weeks
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    B7-H5, SISP1, Gi24, VISTA

  • Source

    Mouse B7-H5, His Tag (B75-M52H7) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Ala 191 (Accession # Q9D659-1).

    Predicted N-terminus: Phe 33

    Request for sequence
  • Molecular Characterization

    B7-H5 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 19.7kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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데이터 표시

  • SDS-PAGE

    B7-H5 SDS-PAGE

    Mouse B7-H5, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

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배경 소개

Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    V-domain Ig suppressor of T-cell activation

  • 카테고리:

  • 상장 의약품 수:

    0 상세

  • 임상 의약품 수:

    8 상세

  • 최고 개발 단계:

    Phase 3 Clinical

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