HEK293/Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Stable Cell Line

• Genetically modified cell lines best reflect MOA (Mechanism of Action)
• Higher activity and larger assay window for robust and reproducible cell-based bioassay
• Comprehensive application data to support assay development and validation
• Full tracible record, stringent quality control and validated cell passage stability
• Parental cell line legally obtained from internationally recognized cell resource bank and commercially licensed
• Global commercial license assistance whenever regulatory filing is required

The HEK293/Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Stable Cell Line was engineered to express the receptors full length human Integrin alpha 4 (Uniprot: P13612-1) and Integrin beta 7 (Uniprot: P26010-1). Surface expression of human Integrin alpha 4 beta 7 was confirmed by flow cytometry.

• Useful for cell-based Integrin alpha 4 beta 7 (ITGA4&ITGB7) binding assay

Adherent

Puromycin (2 μg/mL) + Hygromycin B (20 μg/mL)

DMEM + 20% FBS

Serum-free cell cryopreservation medium

1 vial contains at least 5×10^6 cells in 1 mL serum-free cryopreservation medium

Frozen in liquid nitrogen.

Negative

Negative

See data sheet for detailed culturing and assay protocol.