제품 수집
제품 세부정보
Source
Anti-SARS-CoV-2 Spike RBD Antibody, Human IgG1 (AS113) (Omicron Specific) (SPD-M415) is a chimeric monoclonal antibody recombinantly expressed in HEK293 cells, which combines the variable regions of a mouse monoclonal antibody with human IgG1 constant domains. The variable regions was obtained from a mouse immunized with purified recombinant omicron Spike RBD Protein. The antibody is specific against the Omicron (B.1.1.529/BA.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus and other viral lineages.
Antibody Type
Recombinant Monoclonal
Clone
AS113
Isotype
Human IgG1, Kappa
Host Species
Mouse
Immunogen
Recombinant SARS-CoV-2 Spike RBD (B.1.1.529/Omicron) erived from human 293 cells
Specificity
This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. Cross-reactivity with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1, has not been tested.
Application
ApplicationRecommended Use / PerformanceELISA0.2-2 μg/mLPurification
Protein A purified.
Concentration
Please refer to the Certificate of Analysis (CoA).
Form
Lyophilized
Formulation
Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.
Please contact us for customized product forms or formulations.
Reconstitution
Please refer to the Certificate of Analysis (CoA) for specific instructions.
Shipping
Lyophilized product is shipped at ambient temperature.
Storage
For long term storage, the product should be stored in a lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
Notices
Product Specific Notices: For research use only.
ACRO Quality Management System
고객님도 확인한 상품
데이터 표시
Bioactivity-ELISA
Immobilized SARS-CoV-2 Spike RBD, His Tag (B.1.1.529/Omicron) (Cat. No.SPD-C522e) at 2μg/mL (100μL/well) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Human IgG1 (AS113) (Omicron Specific) (Cat. No. SPD-M415) with a linear range of 0.05-1.56 ng/mL (QC tested).
Protocol
Immobilized SARS-CoV-2 Spike RBD, His Tag (B.1.1.529/Omicron) (Cat. No.SPD-C522e) and SARS-CoV-2 Spike RBD, His Tag (BA.2/Omicron) (Cat. No. SPD-C522g) and SARS-CoV-2 Spike RBD, His Tag (BA.1+L452R/Omicron) (Cat. No. SPD-C522k) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Human IgG1 (AS113) (Omicron Specific) (Cat. No. SPD-M415) with a linear range of 0.049-3.125 ng/mL. The antibody does not bind SARS-CoV-2 Spike RBD WT (Cat. No. SPD-C52H3), Delta (Cat. No. SPD-C52Hh), Beta (Cat. No. SPD-C52Hp), Gamma (Cat. No. SPD-C52Hr), Alpha (Cat. No. SPD-C52Hn) (Routinely tested).
Protocol
사용자 리뷰 댓글 남기기
B***a2023-02-28
좋아요I used this antibody as a control for flow cytometry and it was very reliable. A clear peak shift could be seen with this antibody. When we had questions about what SARS-CoV-2 variants this mAb bound to, ACRO replied quickly and gave us information on the variants we inquired about and then some. ACRO is a company I would purchase from again and my company has used them consistently.- B***a2023-02-28 좋아요I used this antibody as a control for flow cytometry and it was very reliable. When we had questions about what SARS-CoV-2 variants this mAb bound to ACRO replied quickly and gave us information on the variants we inquired about and then some. ACRO is a company I would purchase from again.
E***e2022-05-24 좋아요This omicron protein is a really great product and is high quality. The protein came on time to conduct our experiments and we were able to produce satisfactory results from using this protein. The protein was shipped with dry ice and was in a secure package. We would highly recommend this company and this protein to other labs that are doing omicron research.
FAQ
- product
Can lyophilized proteins remain stable during room-temperature shipping or temporary room-temperature exposure?
In general, lyophilized proteins remain stable during room-temperature shipping or temporary exposure to room-temperature conditions.
Many ACROBiosystems recombinant proteins are supplied in lyophilized (freeze-dried) form. The lyophilization process effectively removes moisture from the product, helping reduce degradation-related reactions and improve protein stability during transportation and storage.
To evaluate the stability of lyophilized proteins under normal temperature conditions, ACROBiosystems conducted a stability study on 11 representative lyophilized protein products at 37°C. The study demonstrated that these proteins maintained good quality stability after storage at 37°C for approximately 20 days. Based on these validation results, temporary room-temperature exposure during shipping or handling is generally not expected to have a significant impact on product quality or downstream application performance.
To ensure optimal long-term stability, products should be stored according to the storage conditions specified in the product Certificate of Analysis (COA) upon receipt.
Supporting Document
배경 소개
프론티어 진행
연락하기
전화
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521
신약 후보물질 라이선싱
