제품 수집
제품 세부정보
Background
Recombinant Monoclonal Anti-PD-1 Antibody, Mouse (2F3) is a PD-1 primary antibody for IHC application. Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
Product Specifications
Host SpeciesMouseIsotypeMouse IgGClone2F3ApplicationIHC-PDilution Ratio1: 200 - 1: 1000FormLiquidClonalityMonoclonalReactivityHumanSynonymsPD1, CD279, PD-1, PDCD1Concentration0.9~1.1 mg/mlSpecificityReact with PD-1 protein on the membrane of target cell/tissuePurification TechProtein APreservationTris buffer, 1% BSAExperiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot. The shelf life is 30 days from the date of opening.ACRO Quality Management System
고객님도 확인한 상품
데이터 표시
Sample Staining Data
Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S238 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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프론티어 진행
의약품 개발 진행- 영어 이름：
Programmed cell death protein 1
- 카테고리：
- 상장 의약품 수：
22 상세
- 임상 의약품 수：
193 상세
- 최고 개발 단계：
Approved
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