描述/背景（Background）

P16 is a member of the Ser/Thr protein kinase family. This protein is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers.

种属（Host Species）

Rabbit

克隆号（Clone）

4A7

适用方法（Application）

IHC

效价（Property）

1：1000

状态（State）

Liquid

阳性对照（Positive Control）

Human Tonsil Tissue

克隆类型（Clonality）

Monoclonal

分子别名（Synonym）

P16, CDK4

研究领域（Research Field）

Cancer Drug Targets

抗体来源（Source）

Rabbit

同种型（Isotype）

IgG

储存（Storage）

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.