Monoclonal NeuN/Rbfox3 Antibody, Mouse IgG1

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NE3-S454-20ul
$80.00
NE3-S454-100ul
$415.00
NE3-S454
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Source

Monoclonal NeuN/Rbfox3 Antibody, Mouse IgG1 is a mouse monoclonal antibody produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse.
Gene Synonyms: Fox-3, Hrn, Hrnbp3, Rbfox3, NeuN, Neuna60, RNA binding protein, fox-1 homolog (C. elegans) 3.

Clone

AS454

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Reactivity

Mouse

Immunogen

Mouse Rbfox3 peptide fused to GST

Specificity

This product is a specific antibody specifically reacts with NeuN/Rbfox3.

Application
Application
Recommended Use
IF
1:500

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS containing 50 mM Glycine and 50 mM Tris, with 40% glycerol as protectant.

Please contact us for customized product forms or formulations.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • Shipped at -20°C. Store at -70°C for 12 months.
Notices

Product Specific Notices: For research use only.

배경 소개

The neuronal nuclear protein (NeuN) is a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. NeuN emerges during early embryogenesis in postmitotic neuroblasts and remains in differentiating and terminally differentiated neurons throughout the whole subsequent ontogeny. NeuN localized in nuclei and perinuclear cytoplasm of most of the neurons in the central nervous system of mammals, has been widely used as a marker for post-mitotic neurons.

Gusel'nikova VV, Korzhevskiy DE. Acta Naturae. 2015;7(2):42-7. PMID: 26085943; PMCID: PMC4463411.

General Notes: FOR RESEARCH USE ONLY.