Biotinylated Monoclonal Anti-Disitamab Antibody, Mouse IgG1 (9E1)

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Cat. No. / Size
Price
Qty
DIB-BMY2558-25ug
$415.00
DIB-BMY2558-200ug
$1705.00
ETA of in-stock products:2 business days

Product Details

  • Source

    Biotinylated Monoclonal Anti-Disitamab Antibody, Mouse IgG1 (9E1) is a recombinant mouse monoclonal antibody expressed in HEK293 cells.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    9E1

  • Isotype

    Mouse IgG1, Kappa

  • Host Species

    Mouse

  • Conjugate

    Biotin

  • Specificity

    Specifically recognizes Human Disitamab; This antibody is a neutralizing antibody.

  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 5%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     Disitamab ELISA

    Immobilized Monoclonal Anti-Disitamab Antibody, Mouse IgG1 (14E10) (Cat. No. DIB-MY2557) at 1 μg/mL, add Disitamab and then add Biotinylated Monoclonal Anti-Disitamab Antibody, Mouse IgG1 (9E1) (Cat. No. DIB-BMY2558) at 1 μg/mL. Detection was performed using HRP-conjugated Streptavidin (Acro, Cat. No. STN-NH913) (QC tested).

    Protocol

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Background

Disitamab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Disitamab works by binding to the HER2 receptor and slowing down cell duplication. Disitamab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay to the extracellular domain of the human epidermal growth factor receptor protein.

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