Recombinant Monoclonal Anti-CD68 Antibody, Rabbit (2D8)

제품 세부정보

Background
Recombinant Monoclonal Anti-CD68 Antibody, Rabbit (2D8) is a CD68 primary antibody for IHC application. Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Host Species	Rabbit
Isotype	Rabbit IgG, Rabbit Kappa
Clone	2D8
Application	IHC-P
Dilution Ratio	1: 500 - 1: 2000
Form	Liquid
Clonality	Monoclonal
Reactivity	Human
Synonyms	DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1
Concentration	0.9~1.1 mg/ml
Specificity	React with CD68 protein on the membrane of target cell/tissue
Purification Tech	Protein A
Preservation	PBS, BSA, Glycerol

Experiment Protocol
LEICA Experiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot.
ACRO Quality Management System

Sample Staining Data
Immunohistochemical analysis of paraffin embedded human colorectal cancer tissue labelled with HGS-S262 at 1:1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.

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