Monoclonal Anti-BCMA Antibody, Mouse IgG1 (AM43)

Source

Monoclonal Anti-BCMA Antibody, Mouse IgG1 (AM43) is a recombinant mouse monoclonal antibody expressed in HEK293 cells.

Antibody Type

Recombinant Monoclonal

Clone

AM43

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Reactivity

Human

Immunogen

BCMA

Specificity

The product specifically targets the extracellular domain of human BCMA protein and inhibits the interaction between BCMA and BAFF (IC50 = 14.79 μg/mL), as well as BCMA and APRIL (IC50 = 17.03 μg/mL).

Application

Cross Verification

Positive: Cross-reactive by ELISA with human, cynomolgus and mouse BCMA protein.

Purification

Protein A purified / Protein G purified.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in Tris (pH 7.5) containing 100 mM Glycine, 25 mM Arginine and 150 mM NaCl, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.

Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

1. QMS(ISO, GMP)
2. Quality Advantages
3. Quality Control Process