Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (MALS verified)

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Availability
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A3R-M575-100ug
$435.00
In Stock - Delivery in 2-3 business days
A3R-M575-1mg (500ug X 2)
$2890.00
In Stock - Delivery in 2-3 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Source

    Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) is a recombinant chimeric monoclonal antibody expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    6F11

  • Isotype

    Human IgG1, Kappa

  • Host Species

    Mouse

  • Reactivity

    Virus

  • Immunogen

    Recombinant Monkeypox virus (strain Zaire-96-I-16) A35R derived from human 293 cells

  • Specificity

    This product is a specific antibody specifically reacts with A35R (MPXV).

  • Application

    Application
    Recommended Usage
    ELISA
    0.2-2 μg/mL
  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 10%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • Bioactivity-ELISA

     A35R (MPXV) ELISA

    Immobilized Monkeypox virus (strain Zaire-96-I-16) A35R , His Tag (Cat. No. A3R-M52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (Cat. No. A3R-M575) with a linear range of 0.1-2 ng/mL (QC tested).

    Protocol
  •  A35R (MPXV) ELISA

    Immobilized Monkeypox virus (Democratic Republic of the Congo) A35R Protein, His Tag (Cat. No. A3R-M52H4) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (Cat. No. A3R-M575) with a linear range of 0.1-3 ng/mL (Routinely tested).

    Protocol
  • Bioactivity-SPR

     A35R (MPXV) SPR

    Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (Cat. No. A3R-M575) captured on Protein A Chip can bind Monkeypox virus (strain Zaire-96-I-16) A35R , His Tag (Cat. No. A3R-M52H3) with an affinity constant of 0.269 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

    Protocol

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배경 소개

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. The envelope glycoprotein A35R on the EV surface has been predicted to influence intercellular diffusion of virions.

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